LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Grape juice increases the BDNF levels but not alter the S100B levels in hippocampus and frontal cortex from male Wistar Rats

DANI, CAROLINE; ANDREAZZA, ANA CRISTINA; GONÇALVES, CARLOS ALBERTO; KAPIZINSKI, FLÁVIO; HENRIQUES, JOÃO A P; SALVADOR, MIRIAN.

An. acad. bras. ciênc; 89 (1), 2017

ABSTRACT Several studies have shown that a high consumption of vegetables and fruits is consistently associated with a low risk of oxidative stress-induced diseases, which includes some degenerative diseases such as amyotrophic lateral sclerosis, Alzheimer and Parkinson. Therefore, the objective of this ...

Antioxidantes/farmacología, Factor Neurotrófico Derivado del Encéfalo/análisis, Factor Neurotrófico Derivado del Encéfalo/efectos de los fármacos, Alimentos Orgánicos, Lóbulo Frontal/química, Lóbulo Frontal/efectos de los fármacos, Jugos de Frutas y Vegetales, Hipocampo/química, Hipocampo/efectos de los fármacos, Distribución Aleatoria, Ratas Wistar, Valores de Referencia, Reproducibilidad de los Resultados, Subunidad beta de la Proteína de Unión al Calcio S100/análisis, Subunidad beta de la Proteína de Unión al Calcio S100/efectos de los fármacos, Vitis/química

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A high-fat diet decreases GABA concentration in the frontal cortex and hippocampus of rats

BACKGROUND: It has been proposed that the γ-aminobutyric acid (GABA) plays a key role in the regulation of food intake and body weight by controlling the excitability, plasticity and the synchronization of neuronal activity in the frontal cortex (FC). It has been also proposed that the high-fat diet (HF...