Transcriptional profiling of uterine leiomyoma rats treated by a traditional herb pair, Curcumae rhizoma and Sparganii rhizoma
Braz. j. med. biol. res; 52 (6), 2019
The aim of this study was to elucidate the concise effects of a traditional herb pair, Curcumae rhizoma-Sparganii rhizoma (CRSR), on uterine leiomyoma (UL) by analyzing transcriptional profiling. The UL rat model was made by intramuscular injection of progesterone and gavage administration of diethylstil...
Curcuma/química, Modelos Animales de Enfermedad, Regulación Neoplásica de la Expresión Génica/efectos de los fármacos, Leiomioma/tratamiento farmacológico, Leiomioma/genética, Leiomioma/metabolismo, Análisis de Secuencia por Matrices de Oligonucleótidos, Extractos Vegetales/farmacología, Radioinmunoensayo, Ratas Sprague-Dawley, Rizoma/química, Factores de Transcripción, Neoplasias Uterinas/tratamiento farmacológico, Neoplasias Uterinas/genética, Neoplasias Uterinas/metabolismo