Insulin Substrate Receptor (IRS) proteins in normal and malignant hematopoiesis
Clinics; 73 (supl.1), 2018
The insulin receptor substrate (IRS) proteins are a family of cytoplasmic proteins that integrate and coordinate the transmission of signals from the extracellular to the intracellular environment via transmembrane receptors, thus regulating cell growth, metabolism, survival and proliferation. The PI3K/A...
Hematopoyesis/fisiología, Proteínas Sustrato del Receptor de Insulina/metabolismo, Proteínas Sustrato del Receptor de Insulina/fisiología, Leucemia Linfoide/metabolismo, Leucemia Linfoide/fisiopatología, Leucemia Mieloide/metabolismo, Leucemia Mieloide/fisiopatología, Transducción de Señal/fisiología