Quimioterapia intensiva asociada a imatinib en leucemia linfoblástica aguda del adulto, Philadelphia positivo. Experiencia en un hospital público
Rev. méd. Chile; 149 (9), 2021
Background: Before the advent of tyrosine kinase inhibitors (TKIs), patients with Philadelphia-positive Acute Lymphoblastic Leukemia (Ph+ALL) had a poor prognosis. The association of TKIs to intensive chemotherapy (CT) improved outcome. Aim: To evaluate results of an intensive CT protocol including TKI i...
Cromosoma Filadelfia, Leucemia-Linfoma Linfoblástico de Células Precursoras B/diagnóstico, Leucemia-Linfoma Linfoblástico de Células Precursoras/tratamiento farmacológico, Mesilato de Imatinib/uso terapéutico, Neoplasia Residual/diagnóstico, Neoplasia Residual/tratamiento farmacológico, Inhibidores de Proteínas Quinasas/uso terapéutico