Results: 2

The chondrotoxic and apoptotic effects of levobupivacaine and bupivacaine on the rabbit knee joint

Rev. bras. anestesiol; 68 (6), 2018
Abstract Background: A single dose injection or continuous infusion of local anesthetics into the joint space is considered to be a well-defined analgesia technique. The aim of this study was to investigate the chondrotoxic and apoptotic effects of single-dose intra-articular injection of levobupivacain...

Neurotoxic effects of levobupivacaine and fentanyl on rat spinal cord

Rev. bras. anestesiol; 65 (1), 2015
BACKGROUND: The purpose of the study was to compare the neurotoxic effects of intrathecally administered levobupivacaine, fentanyl and their mixture on rat spinal cord. METHODS: In experiment, there were four groups with medication and a control group. Rats were injected 15 µL saline or fentanyl 0.0005 ...