Cytotoxicity, nitric oxide and acetylcholinesterase inhibitory activity of three limonoids isolated from Trichilia welwitschii (Meliaceae)
Biol. Res; 48 (), 2015
BACKGROUND: Limonoids are highly oxygenated compounds with a prototypical structure. Their occurrence in the plant kingdom is mainly confined to plant families of Meliaceae and Rutaceae. Owing to their wide range of pharmacological and therapeutic properties, this study was aimed at investigating the pot...
Inhibidores de la Colinesterasa/farmacología, Limoninas/farmacología, Meliaceae/química, Óxido Nítrico/antagonistas & inhibidores, Antiinflamatorios/farmacología, Proliferación Celular/efectos de los fármacos, Lactonas/análisis, Lactonas/farmacología, Limoninas/análisis, Limoninas/aislamiento & purificación, Macrófagos/efectos de los fármacos, Óxido Nítrico/análisis, Chlorocebus aethiops, Concentración 50 Inhibidora, Dosificación Letal Mediana, Lipopolisacáridos, Células RAW 264.7, Células Vero