Results: 4

Artesunate promotes Th1 differentiation from CD4+ T cells to enhance cell apoptosis in ovarian cancer via miR-142

Braz. j. med. biol. res; 52 (5), 2019
The aim of this study was to evaluate the influence of artesunate on Th1 differentiation and its anti-tumor effect on ovarian cancer. A Murine ovarian cancer model was established by ID8 cells transplantation. The expression of miR-142 and Sirt1 proteins in peripheral CD4+ T cells were quantified with qR...

CD4+CD69+ T cells and CD4+CD25+FoxP3+ Treg cells imbalance in peripheral blood, spleen and peritoneal lavage from pristane-induced systemic lupus erythematosus (SLE) mice

Adv Rheumatol; 59 (), 2019
Abstract Background: Adaptive immune cells, including CD4+CD69+ and CD4+CD25+FoxP3+ regulatory T (Treg) cells, are important for maintaining immunological tolerance. In human systemic lupus erythematosus (SLE), CD4+CD25+FoxP3+ Treg cells are reduced, whereas CD69 expression is increased, resulting in a ...

T lymphocytes and macrophages in the intestinal tissues of dogs infected with Leishmania infantum

Abstract This study was about a semi-quantitative analysis of T lymphocytes (CD4+ and CD8+, FoxP3+ regulatory T cells), and macrophages in the gut wall of dogs naturally infected with Leishmania infantum. Thirteen dogs were divided into three groups: group 1 (G1, n=5), dogs with canine visceral leishmani...

Citometría capilar volumétrica: Nueva alternativa en la determinación de subpoblaciones linfocitarias
Volumetric capillary cytometry: New alternative in determination of lymphocyte subpopulations

Rev. mex. patol. clín; 46 (2), 1999
La determinación de células T CD4+ y CD8+ por citometría de flujo es uno de los métodos de laboratorio de mayor utilidad en el manejo de los pacientes infectados con los virus de la inmunodeficiencia humana; sin embargo, su complejidad técnica e instrumental y su elevado costo han limitado su empleo...