Abstract Background: The treatment of cutaneous leishmaniasis is a challenge. A better understanding of the in situ mechanisms involved in the evolution and cure of the disease is essential for the development of new therapies. Objective: Correlate histopathological and immunological characteristics of...
Even though the mechanisms that mediate essential hypertension (HT) are not fully understood, an immunological-inflammatory mechanism could be the common pathway for diverse pathophysiological mechanisms. We analyze in a simplified way the participation of the immune system in HT. T lymphocytes (TL) and ...
The interaction of HIV-1, human leukocyte antigen (HLA), and elite controllers (EC) compose a still intricate triad. Elite controllers maintain a very low viral load and a normal CD4 count, even without antiretrovirals. There is a lot of diversity in HIV subtypes and HLA alleles. The most common subtype ...
SUMMARY BACKGROUND: The COVID-19 pandemic has affected the entire world, posing a serious threat to human health. T cells play a critical role in the cellular immune response against viral infections. We aimed to reveal the relationship between T cell subsets and disease severity. METHODS: 40 COVID-19 ...
Resumen En el presente trabajo informamos la afectación de parámetros inmunológicos durante la etapa grave de la infección y luego de alcanzar la recuperación clínica en un paciente autóctono del Noroeste argentino con leishmaniasis visceral causada por Leishmania (Leishmania) infantum. Detectamos...
Bastos, Marta Ferreira;
Matias, Manuella de Sousa Toledo;
Alonso, Angélica Castilho;
Silva, Léia Cristina Rodrigues;
de Araújo, Adriana Ladeira;
Silva, Paulo Roberto;
Benard, Gil;
Bocalini, Danilo Sales;
Steven Baker, Julien;
Leme, Luiz Eugênio Garcez.
OBJECTIVES: Immunosenescence is an age-associated change characterized by a decreased immune response. Although physical activity has been described as fundamental for maintaining the quality of life, few studies have evaluated the effects of different levels of exercise on telomere length in aged popula...
SUMMARY OBJECTIVE To investigate the relations of T lymphocytes, cytokines, immunoglobulin E, and nitric oxide with otitis media with effusion (OME) in children and their clinical significances. METHODS Fifty children with OME treated in our hospital were enrolled in the study (observation group). Fi...
Linfocitos T CD4-Positivos,
Linfocitos T CD8-positivos,
Estudios de Casos y Controles,
Citocinas/sangre,
Citometría de Flujo,
Inmunoglobulina E/sangre,
Recuento de Linfocitos,
Óxido Nítrico/sangre,
Otitis Media con Derrame/sangre,
Valores de Referencia,
Membrana Timpánica/metabolismo
ABSTRACT Background: HIV infection harms adaptive cellular immunity mechanisms. Long-term virological control by combined antiretroviral therapy (cART) reduces the risk of mycobacterial infections. Thus, we aimed to study cellular responses to mycobacterial antigens in 20 HIV-infected adolescents with a...
Infecciones Oportunistas Relacionadas con el SIDA/inmunología,
Fármacos Anti-VIH/uso terapéutico,
Presentación de Antígeno/inmunología,
Antígenos Bacterianos/efectos de los fármacos,
Antígenos Bacterianos/inmunología,
Biomarcadores/sangre,
Linfocitos T CD8-positivos/inmunología,
Estudios Transversales,
Inmunofenotipificación,
Transmisión Vertical de Enfermedad Infecciosa,
Mycobacterium tuberculosis/inmunología,
Estudios Prospectivos,
Receptores de Antígenos de Linfocitos T alfa-beta/inmunología,
Tuberculosis/inmunología
Abstract: Background: Pityriasis rosea is a common papulosquamous disorder. However, its etiology and pathogenesis remain unclear. Objective: We investigate the types of inflammatory cells infiltrating the lesional skin of pityriasis rosea and demonstrate whether T-cell-mediated immunity is involved in...
Biopsia,
Complejo CD3/análisis,
Linfocitos T CD4-Positivos/patología,
Linfocitos T CD8-positivos/patología,
Inmunidad Celular,
Inmunohistoquímica,
Antígenos Comunes de Leucocito/análisis,
Pitiriasis Rosada/inmunología,
Pitiriasis Rosada/patología,
Valores de Referencia,
Coloración y Etiquetado,
Subgrupos de Linfocitos T/inmunología,
Subgrupos de Linfocitos T/patología,
Factores de Tiempo
Abstract INTRODUCTION: Tropical spastic paraparesis/HTLV-1 associated myelopathy (TSP/HAM) is a disease caused by human T-cell lymphotropic virus type 1 (HTLV-I) that mainly infects CD4 T cells-for example, those of the CD4+CD25hiFOXP3+ [Treg] phenotype-where it inhibits forkhead box protein P3 (FOXP3)...
Carga Viral,
Linfocitos T Reguladores/virología,
Linfocitos T Reguladores/inmunología,
Paraparesia Espástica Tropical/virología,
Paraparesia Espástica Tropical/inmunología,
Interferón gamma/inmunología,
Linfocitos T CD8-positivos/virología,
Linfocitos T CD8-positivos/inmunología,
Linfocitos T CD4-Positivos/virología,
Linfocitos T CD4-Positivos/inmunología,
Linfocitos B Reguladores/virología,
Linfocitos B Reguladores/inmunología
