Even though the mechanisms that mediate essential hypertension (HT) are not fully understood, an immunological-inflammatory mechanism could be the common pathway for diverse pathophysiological mechanisms. We analyze in a simplified way the participation of the immune system in HT. T lymphocytes (TL) and ...
BACKGROUND Anisakis simplex antigens present immunomodulatory properties by the induction of tolerogenic dendritic cells (DCs) in mice. OBJECTIVES To study the capacity of DCs stimulated with A. simplex excretory-secretory (ES) or crude extract (CE) to generate Tregs. To investigate in vitro effects of...
A large number of cancer patients relapse after chemotherapeutic treatment. The immune system is capable of identifying and destroying cancer cells, so recent studies have highlighted the growing importance of using combinatorial chemotherapy and immunotherapy. However, many patients have innate or acqui...
OBJECTIVES: This study intended to explore the effect of T regulatory cells (Tregs) in the perinatal liver against LPS-induced inflammation in a preterm birth mouse model. Moreover, the role of adoptive Tregs on the inflammatory response induced by LPS was also studied. METHODS: Female BALB/C mice were ...
Abstract Regulatory T (Treg) cells can suppress antitumor immune response, but little is known about possible age-related differences in the number of these cells in the microenvironment of oral tongue squamous cell carcinoma (OTSCC). The aim of this study was to determine the number of FoxP3+ Treg cells...
Bergamini, Mariana Lobo;
Mardegan, Andressa Pinto;
DE Rosa, Catharina Simioni;
Palmieri, Michelle;
Sarmento, Dmitry José de Santana;
Hiraki, Karen Renata Nakamura;
Costa, André Luiz Ferreira;
HassÉus, Bengt;
Jonasson, Peter;
Braz-Silva, Paulo Henrique.
Abstract Asymptomatic Apical Periodontitis is essentially an inflammatory disease of microbial aetiology. Association and function of the cell components involved, or specific inductive factors and growth mediators associated with development, maintenance and resolution of the periapical lesions are stil...
ABSTRACT Objective To analyze and compare the expression of Toll-like receptors by regulatory T cells present in the peritoneal fluid of patients with and without endometriosis. Methods Regulatory T cells were isolated from peritoneal fluid of women with and without endometriosis, collected during su...
Líquido Ascítico/inmunología,
Líquido Ascítico/patología,
Índice de Masa Corporal,
Estudios de Casos y Controles,
Endometriosis/inmunología,
Endometriosis/patología,
Endometrio/inmunología,
Endometrio/patología,
Valores de Referencia,
Reacción en Cadena de la Polimerasa de Transcriptasa Inversa,
Estadísticas no Paramétricas,
Linfocitos T Reguladores/química,
Linfocitos T Reguladores/inmunología,
Receptores Toll-Like/análisis,
Escala Visual Analógica
Resumen El lupus eritematoso generalizado (LEG) es una enfermedad autoinmune crónica caracterizada por la pérdida de la tolerancia a los antígenos propios y la síntesis de diferentes autoanticuerpos con la formación y depósito de complejos inmunes y el daño de múltiples órganos. Las células T r...
Abstract INTRODUCTION: Tropical spastic paraparesis/HTLV-1 associated myelopathy (TSP/HAM) is a disease caused by human T-cell lymphotropic virus type 1 (HTLV-I) that mainly infects CD4 T cells-for example, those of the CD4+CD25hiFOXP3+ [Treg] phenotype-where it inhibits forkhead box protein P3 (FOXP3)...
Carga Viral,
Linfocitos T Reguladores/virología,
Linfocitos T Reguladores/inmunología,
Paraparesia Espástica Tropical/virología,
Paraparesia Espástica Tropical/inmunología,
Interferón gamma/inmunología,
Linfocitos T CD8-positivos/virología,
Linfocitos T CD8-positivos/inmunología,
Linfocitos T CD4-Positivos/virología,
Linfocitos T CD4-Positivos/inmunología,
Linfocitos B Reguladores/virología,
Linfocitos B Reguladores/inmunología
Introdução: A suplementação com ácido fólico (AF) é recomendada em algumas condições para evitar a deficiência de folato, como para mulheres no período periconcepcional e durante a gestação. Atualmente, existe uma preocupação quanto ao consumo excessivo de AF pela população pelo uso de s...
