LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Linderae radix ethanol extract attenuates alcoholic liver injury via attenuating inflammation and regulating gut microbiota in rats

Lou, Zhaohuan; Wang, Junwei; Chen, Yingjun; Xu, Chandi; Chen, Xinyi; Shao, Tiejuan; Zhang, Kena; Pan, Hongying.

Braz. j. med. biol. res; 52 (6), 2019

This study aimed to explore the influence of gut microbiota alterations induced by Linderae radix ethanol extract (LREE) on alcoholic liver disease (ALD) in rats and to study the anti-inflammatory effect of LREE on ALD through the lipopolysaccharide (LPS) toll-like receptor 4 (TLR4)-nuclear factor kappa ...

Citocinas/sangre, Modelos Animales de Enfermedad, Microbioma Gastrointestinal/efectos de los fármacos, Inflamación/prevención & control, Lindera/química, Lipopolisacáridos/sangre, Hígado/ultraestructura, Hepatopatías Alcohólicas/diagnóstico por imagen, Hepatopatías Alcohólicas/prevención & control, Extractos Vegetales/farmacología, Raíces de Plantas/química, Proteínas Serina-Treonina Quinasas/sangre, Ratas Sprague-Dawley, Receptor Toll-Like 4/sangre

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Obese with higher FNDC5/Irisin levels have a better metabolic profile, lower lipopolysaccharide levels and type 2 diabetes risk

Bonfante, Ivan Luiz Padilha; Chacon-Mikahil, Mara Patricia Traina; Brunelli, Diego Trevisan; Gáspari, Arthur Fernandes; Duft, Renata Garbellini; Oliveira, Alexandre Gabarra; Araujo, Tiago Gomes; Saad, Mario Jose Abdalla; Cavaglieri, Cláudia Regina.

Arch. endocrinol. metab. (Online); 61 (6), 2017

ABSTRACT Objective: Thus, the aim of this study was to compare if higher or smaller fibronectin type 3 domain-containing protein 5 (FNDC5)/irisin levels are associated with inflammatory and metabolic markers, caloric/macronutrient intake, physical fitness and type 2 diabetes mellitus (T2DM) risk in obes...

Biomarcadores/sangre, Presión Sanguínea/fisiología, Capacidad Cardiovascular/fisiología, Estudios Transversales, Diabetes Mellitus Tipo 2/sangre, Diabetes Mellitus Tipo 2/etiología, Diabetes Mellitus Tipo 2/fisiopatología, Ingestión de Energía/fisiología, Prueba de Esfuerzo, Fibronectinas/sangre, Lipopolisacáridos/sangre, Obesidad/sangre, Obesidad/complicaciones, Obesidad/fisiopatología, Factores de Riesgo

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Immune development in HIV-exposed uninfected children born to HIV-infected women

Miyamoto, Maristela; Gouvêa, Aída FTB; Ono, Erika; Succi, Regina Célia M; Pahwa, Savita; Moraes-Pinto, Maria Isabel de.

Rev. Inst. Med. Trop. Säo Paulo; 59 (), 2017

ABSTRACT Immunological and clinical findings suggestive of some immune dysfunction have been reported among HIV-exposed uninfected (HEU) children and adolescents. Whether these defects are persistent or transitory is still unknown. HEU pediatric population at birth, 12 months, 6-12 years were evaluated i...

Biomarcadores/sangre, Recuento de Linfocito CD4, Estudios de Casos y Controles, Citocinas/sangre, Citocinas/inmunología, Citometría de Flujo, Infecciones por VIH/inmunología, Memoria Inmunológica, Receptores de Lipopolisacáridos/sangre, Receptores de Lipopolisacáridos/inmunología, Lipopolisacáridos/sangre, Lipopolisacáridos/inmunología, Exposición Materna, Complicaciones Infecciosas del Embarazo/inmunología, Valores de Referencia, Factores de Tiempo

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