Cholesteryl ester transfer protein inhibitory oxoacetamido-benzamide derivatives: Glide docking, pharmacophore mapping, and synthesis
Braz. J. Pharm. Sci. (Online); 58 (), 2022
Abstract Dyslipidemia is an abnormal lipid profile associated with many common diseases, including coronary heart disease and atherosclerosis. Cholesteryl ester transfer protein (CETP) is a hydrophobic plasma glycoprotein that is responsible for the transfer of cholesteryl ester from high-density lipopro...
Proteínas de Transferencia de Ésteres de Colesterol/antagonistas & inhibidores, Dislipidemias/complicaciones, Benzamidas/efectos adversos, Concentración 50 Inhibidora, Enfermedad Coronaria/patología, Lipoproteínas HDL/clasificación, Lipoproteínas LDL/clasificación, Técnicas In Vitro/métodos, Ésteres del Colesterol