LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Mechanisms involved in anti-aging effects of guarana (Paullinia cupana) in Caenorhabditis elegans

Arantes, L P; Machado, M L; Zamberlan, D C; da Silveira, T L; da Silva, T C; da Cruz, I B M; Ribeiro, E E; Aschner, M; Soares, F A A.

Braz. j. med. biol. res; 51 (9), 2018

Guarana (Paullinia cupana) is habitually ingested by people in the Amazon region and is a key ingredient in various energy drinks consumed worldwide. Extension in longevity and low prevalence of chronic age-related diseases have been associated to habitual intake of guarana. Anti-aging potential of guara...

Envejecimiento/efectos de los fármacos, Antioxidantes/aislamiento & purificación, Antioxidantes/farmacología, Caenorhabditis elegans/efectos de los fármacos, Caenorhabditis elegans/fisiología, Longevidad/efectos de los fármacos, Paullinia/química, Extractos Vegetales/farmacología, Reacción en Cadena de la Polimerasa de Transcriptasa Inversa, Factores de Tiempo

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Ilex paraguariensis extracts extend the lifespan of Drosophila melanogaster fed a high-fat diet

Colpo, A C; Lima, M E; da Rosa, H S; Leal, A P; Colares, C C; Zago, A C; Salgueiro, A C F; Bertelli, P R; Minetto, L; Moura, S; Mendez, A S L; Folmer, V.

Braz. j. med. biol. res; 51 (2), 2018

Studies have suggested that total energy intake and diet composition affect lifespan and ageing. A high-fat diet induces oxidative stress and affects the development of diseases. In contrast, antioxidants are capable of reducing its harmful effects. Yerba mate beverages are an important source of antioxi...

Antioxidantes/farmacología, Dieta Alta en Grasa, Drosophila melanogaster/crecimiento & desarrollo, Drosophila melanogaster/fisiología, Ilex paraguariensis/química, Longevidad/efectos de los fármacos, Longevidad/fisiología, Estrés Oxidativo/efectos de los fármacos, Estrés Oxidativo/fisiología, Extractos Vegetales/farmacología

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Selenocysteine modulates resistance to environmental stress and confers anti-aging effects in C. elegans

Kim, Jun-Sung; Kim, So-Hyeon; Park, Sang-Kyu.

Clinics; 72 (8), 2017

OBJECTIVE: The free radical theory of aging suggests that cellular oxidative damage caused by free radicals is a leading cause of aging. In the present study, we examined the effects of a well-known anti-oxidant amino acid derivative, selenocysteine, in response to environmental stress and aging using Ca...

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