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Development and evaluation of sustained release losartan potassium matrix tablet using kollidon SR as release retardant

Braz. j. pharm. sci; 48 (4), 2012
The present study was undertaken to develop sustained release (SR) matrix tablets of losartan potassium, an angiotensin-II antagonist for the treatment of hypertension. The tablets were prepared by direct compression method, along with Kollidon SR as release retardant polymer. The amount of losartan pota...