Results: 2

Renal expression of AQP1 in the high-fat nutritional obesity of rat

Wang, Jinbao; Yang, Wen; Wang, Pei; Wu, Jing; Wang, Zhisheng; Yang, Mengmeng; Jin, Xueqin.

Int. j. morphol; 37 (2), 2019

AQP1 plays an essential role in maintaining body water balance. In the kidney, AQP1 is localized to the apical and basolateral membrane of epithelial cells in the proximal tubule and descending thin limb of Ansa nephroni (Henle's loop) where it reabsorbs the vast majority of filtered water. The growing e...

Dieta Alta en Grasa, Acuaporina 1/metabolismo, Riñón/patología, Médula Renal/patología, Inmunohistoquímica, Ratas Sprague-Dawley, Riñón/metabolismo

Fulltext

Expression of V2R and AQPs in the renal medulla of high-fat nutritional obesity of rat

Wang, Jinbao; Wang, Pei; Wang, Zhisheng; Ran, Linwu; Yang, Li; Yang, Wen.

Int. j. morphol; 37 (2), 2019

Recent evidence has indicated that adipose tissue produces bioactive substances that contribute to obesity-related kidney disease, altering the renal function and structure. Eight of the AQPs are expressed in the kidney, where several of them contribute to water absorption and maintenance of body water b...

Obesidad, Enfermedades Renales/metabolismo, Médula Renal/patología, Acuaporinas/metabolismo, Acuaporina 1/metabolismo, Acuaporina 2/metabolismo, Dieta Alta en Grasa, Receptores de Vasopresinas/metabolismo, Inmunohistoquímica, Microscopía, Médula Renal/metabolismo, Ratas Sprague-Dawley

Fulltext