Results: 17

Mecanosensores en el cambio de fenotipo de la musculatura lisa vascular

Rev. chil. cardiol; 40 (3), 2021
Resumen: Introducción: Las células de la musculatura lisa vascular (CMLV) se caracterizan por mantener cierto grado de desdiferenciación, variando su fenotipo entre el contráctil y el secretor, de acuerdo con las necesidades del tejido, y el contráctil predominante en condiciones fisiológicas. Cual...

Efecto del 4-Clorofenol sobre el músculo liso vascular de aorta abdominal de ratas Wistar
Effect of 4-Chlorophenol on the vascular smooth muscle of the abdominal aorta of Wistar rats

Introducción: Uno de los derivados de los clorofenoles más utilizado en Estomatología, lo constituye el p-clorofenol (4-clorofenol), empleado como agente antibacteriano en la desinfección del conducto radicular durante el tratamiento pulporradicular. Son escasos los reportes científicos sobre sus ef...

Dinámica contráctil espontánea del músculo liso vascular de la arteria carótida externa
Spontaneous contractile dynamics of the vascular smooth muscle of the external carotid artery

Medisan; 25 (3), 2021
Introducción: La carótida externa es una arteria muscular que irriga todos los componentes del sistema masticatorio, por lo que la regulación de la dinámica contráctil de su músculo liso vascular es imprescindible para garantizar el tono y el flujo sanguíneo tisular y modular la respuesta inflamat...

Dinámica contráctil inducida por p-clorofenol alcanforado en anillos aórticos de ratas Wistar

Rev inf cient; 100 (5), 2021
Introducción: El p-clorofenol alcanforado es un derivado clorofenólico de uso común como medicación intraconducto en Endodoncia. Son escasos los reportes científicos sobre sus efectos en la musculatura lisa vascular arterial y la regulación del flujo sanguíneo local. Objetivo: Determinar el efecto...

Cbfa1 expression in vascular smooth muscle cells may be elevated by increased nitric oxide/iNOS

J. bras. nefrol; 42 (3), 2020
ABSTRACT Introduction: Vascular calcification is a common complication of chronic kidney disease. Osteoblast differentiation factor (Cbfa1) is present in histologic sections of arteries from patients with end-stage renal disease. Vascular smooth muscle cells (VSMC) can dedifferentiate to osteoblast-lik...

Effects of NO/cGMP inhibitors in a rat model of anaphylactoid shock

Braz. j. med. biol. res; 53 (3), 2020
Anaphylactic shock can be defined as an acute syndrome, and it is the most severe clinical manifestation of allergic diseases. Anaphylactoid reactions are similar to anaphylactic events but differ in the pathophysiological mechanism. Nitric oxide (NO) inhibitors during anaphylaxis suggest that NO might d...

LncRNA HCG11 regulates proliferation and apoptosis of vascular smooth muscle cell through targeting miR-144-3p/FOXF1 axis in atherosclerosis

Biol. Res; 53 (), 2020
BACKGROUND: Atherosclerosis (AS) is the main pathological basis of coronary heart disease, cerebral infarction and peripheral vascular disease, which seriously endanger people's life and health. In recent years, long non-coding RNA (lncRNA) has been found to be involved in gene expression regulation, but...

Effects of in vitro amitriptyline, fluoxetine, tranylcypromine and venlafaxine on saphenous vein grafts

Abstract Objective: In this study, we aimed to examine the effects of amitriptyline, fluoxetine, tranylcypromine and venlafaxine on saphenous vein grafts in coronary artery bypass graft surgeries. Methods: 59 patients (40 males and 19 females; mean age 65.1 years, distribution: 45-84 years) who had cor...

Tyrosine phosphorylation of Kv1. 5 is upregulated in intrauterine growth retardation rats with exaggerated pulmonary hypertension

Braz. j. med. biol. res; 50 (11), 2017
Intrauterine growth retardation (IUGR) is associated with the development of adult-onset diseases, including pulmonary hypertension. However, the underlying mechanism of the early nutritional insult that results in pulmonary vascular dysfunction later in life is not fully understood. Here, we investigate...

A spleen tyrosine kinase inhibitor attenuates the proliferation and migration of vascular smooth muscle cells

Biol. Res; 50 (), 2017
BACKGROUND: Pathologic vascular smooth muscle cell (VSMC) proliferation and migration after vascular injury promotes the development of occlusive vascular disease. Therefore, an effective chemical agent to suppress aberrant proliferation and migration of VSMCs can be a potential therapeutic modality for ...