Targeting of temozolomide using magnetic nanobeads: an in vitro study
Braz. J. Pharm. Sci. (Online); 56 (), 2020
Temozolomide, a chemotherapeutic drug that is often administered for the treatment of brain cancer has severe side effects and a poor aqueous solubility. In order to decrease the detrimental effect of the drug over healthy cells, a novel drug delivery vehicle was developed where the therapeutic drug was ...
Técnicas In Vitro/instrumentación, Temozolomida/análisis, Quitosano/antagonistas & inhibidores, Óxido Ferrosoférrico/farmacología, Ciclodextrinas/farmacología, Campos Magnéticos/efectos adversos, Magnetismo/clasificación, Nanopartículas de Magnetita/efectos adversos, Neoplasias Encefálicas, Preparaciones Farmacéuticas/administración & dosificación