Large Accumulation of Collagen and Increased Activation of Mast Cells in Hearts of Mice with Hyperlipidemia
Arq. bras. cardiol; 109 (5), 2017
Abstract Background: Hyperlipidemia, which is characterized by an elevation of lipids in the bloodstream, is a major risk factor for cardiac disease. Objectives: The present study investigated the role of fibrosis in the progression of hyperlipidemia in the mice heart, and whether mast cell activation ...
Western Blotting, Colágeno/metabolismo, Dieta Alta en Grasa/efectos adversos, Modelos Animales de Enfermedad, Fibrosis, Hiperlipidemias/etiología, Hiperlipidemias/metabolismo, Hiperlipidemias/patología, Inmunohistoquímica, Mastocitos/química, Mastocitos/metabolismo, Ratones Endogámicos C57BL, Miocardio/metabolismo, Miocardio/patología