Results: 2

Macromolecular confinement of therapeutic protein in polymeric particles for controlled release: insulin as a case study

Guerreiro, Luiz Henrique; Silva, Daniel da; Girard-Dias, Wendell; Mascarenhas, Camile Moreira; Miranda, Kildare; Sola-Penna, Mauro; Ricci Júnior, Eduardo; Lima, Luís Mauricio Trambaioli da Rocha e.

Braz. J. Pharm. Sci. (Online); 53 (2), 2017

ABSTRACT Sustained release systems for therapeutic proteins have been widely studied targeting to improve the action of these drugs. Molecular entrapping of proteins is particularly challenging due to their conformational instability. We have developed a micro-structured poly-epsilon-caprolactone (PCL) p...

Insulina/análisis, Liberación de Fármacos/fisiología, Material Particulado/farmacología, Microscopía Electrónica/22074, Hipoglucemiantes/farmacología, Preparaciones Farmacéuticas/administración & dosificación, Diabetes Mellitus/prevención & control

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Influence of high-dose gamma radiation and particle size on antioxidant properties of Maize ( Zea mays L. ) flour

Nawaz, Haq; Shad, Muhammad Aslam; Rehman, Tanzila; Ramzan, Ayesha.

Braz. j. pharm. sci; 52 (4), 2016

ABSTRACT Influence of high-dose gamma radiation and particle size on antioxidant properties of maize (Zea mays L.) flour was studied using response surface methodology. A central composite design based on three levels of each of particle size, in terms of mesh number (40, 60 and 80 meshes), and gamma ra...

Zea mays/clasificación, Antioxidantes/análisis, Material Particulado/farmacología, Irradiación de Alimentos/efectos adversos

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