O dano capilar causado pelo descolorimento oxidativo é muito intenso, sendo que dois fatores são responsáveis por essa ação: primeiro, a ação direta e danosa do oxidante em diversas estruturas capilares e segundo, o dano oxidativo primário facilita o dano causado por outros agentes físicos (luz,...
ABSTRACT Objective: To compare and evaluate the clinical efficacy of diode laser and cryosurgery for treating melanin pigmentation of gingiva. Material and Methods: A total of twenty-five subjects with physiological gingival pigmentation on the facial aspect of both maxillary and mandibular anterior ar...
Ribeiro, Priscilla Tobias;
Pedrosa, Tatiana do Nascimento;
Chaves, Francisco Celio Maia;
José Quintans-Júnior, Lucindo;
Araújo, Adriano Antunes de Souza;
Vasconcellos, Marne Carvalho de;
Maria-Engler, Silvya Stuchi;
Silva, Cláudia Cândida;
Silva, Felipe Moura Araújo da;
Koolen, Héctor Henrique Ferreira;
Lima, Emerson Silva;
Lima, Ádley Antonini Neves de.
Abstract Passiflora nitida Kunth, an Amazonian Passiflora species, is little studied, although the specie’s high biological potential. Herein the plant’s pharmacognostic characterization, extract production, antioxidant potential evaluation, and application of this extract in cosmetic products is rep...
Passiflora/clasificación,
Extractos Vegetales/análisis,
Hojas de la Planta/efectos adversos,
Monofenol Monooxigenasa/antagonistas & inhibidores,
Cosméticos/clasificación,
Antioxidantes/efectos adversos,
Compuestos Fenólicos,
Melaninas,
Rayos X/efectos adversos,
Termogravimetría/métodos,
Rastreo Diferencial de Calorimetría/métodos
SUMMARY: Human skin melanin was stained using the Fontana's silver nitrate method and Schmorl method. The results showed that, in the Fontana's silver nitrate method, melanin and silver-bound cells were black and other tissues were red. When stained using the Schmorl method, effects on melanin differed b...
Abstract Background: The independent role of solar radiation in the differential melanogenesis between melasma and adjacent skin is unknown. Objectives: To assess the melanogenic responses of skin with facial melasma and of the adjacent skin to UVB, UVA, and visible light, in an ex vivo model. Methods...
Las pigmentaciones de la cavidad oral son comunes, éstas pueden
representar diversas entidades clínicas, desde cambios fisiológicos
hasta cambios malignos. Las pigmentaciones en la encía se conocen
como pigmentaciones melánicas o melanosis gingival; en la encía se
observan como tinciones oscuras oc...
Criptococose é uma doença grave que afeta tanto imunocomprometidos quanto imunocompetentes, com isso analisar a virulência é fundamental para novas terapêuticas. Objetivo: Analisar a capacidade de virulência e susceptibilidade aos antifúngicos de Cryptococcus spp. isolados de líquor de pacientes ...
Antifúngicos/análisis,
Criptococosis/virología,
Fagocitosis,
Melaninas/análisis,
Neutrófilos/virología,
Preparaciones Farmacéuticas,
Ureasa/orina,
Factores de Virulencia/análisis,
Anfotericina B/análisis,
Cryptococcus gattii/virología,
Itraconazol,
Miconazol,
Voriconazol,
Agar/análisis,
Levaduras/virología,
Cryptococcus neoformans/virología,
Cápsulas/análisis
Abstract Background: Organoid cultures are primary cultures that maintain architectural characteristics and the relationships between cells, as well as the extracellular matrix. They are alternatives for pathophysiological or therapeutic investigation rather than animal and in vitro tests. Objective: D...
Biopsia,
Técnicas de Cultivo de Célula/normas,
Células Cultivadas,
Expresión Génica,
Luz,
Melaninas/biosíntesis,
Melaninas/efectos de la radiación,
Organoides/efectos de la radiación,
Dosis de Radiación,
Reacción en Cadena en Tiempo Real de la Polimerasa,
Reproducibilidad de los Resultados,
Nitrato de Plata,
Pigmentación de la Piel/efectos de la radiación,
Factores de Tiempo,
Rayos Ultravioleta
Vitiligo is an acquired pigmentary disorder resulting from selective destruction of melanocytes. Emerging studies have suggested that T helper cell 17 (Th17) is potentially implicated in vitiligo development and progression. It was recently discovered that metabotropic glutamate receptor 4 (mGluR4) can m...
Células de la Médula Ósea/citología,
Diferenciación Celular/fisiología,
Células Dendríticas/citología,
Citometría de Flujo,
Melaninas/biosíntesis,
Melanocitos/citología,
Ratones Endogámicos C57BL,
ARN Interferente Pequeño/inmunología,
Receptores de Glutamato Metabotrópico/fisiología,
Células Th17/citología,
Células Th17/inmunología,
Vitíligo/genética,
Vitíligo/inmunología
BACKGROUND Acinetobacter baumannii outbreaks have been associated with pandemic International Clones (ICs), but the virulence factors involved with their pathogenicity are sparsely understood. Pigment production has been linked with bacterial pathogenicity, however, this phenotype is rarely observed in A...
Infecciones por Acinetobacter/microbiología,
Acinetobacter baumannii/efectos de los fármacos,
Acinetobacter baumannii/genética,
Acinetobacter baumannii/aislamiento & purificación,
Antibacterianos/farmacología,
Vías Biosintéticas/genética,
Electroforesis en Gel de Campo Pulsado,
Melaninas,
Pruebas de Sensibilidad Microbiana,
Tipificación de Secuencias Multilocus,
Pandemias,
beta-Lactamasas