LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Standardization of organoid culture for evaluation of melanogenesis induced by UVB, UVA and visible light

Olivatti, Thainá Oliveira Felicio; Alcantara, Giovana Piteri; Lemos, Ana Cláudia Cavalcante Espósito; Silva, Márcia Guimarães da; Miot, Hélio Amante.

An. bras. dermatol; 95 (1), 2020

Abstract Background: Organoid cultures are primary cultures that maintain architectural characteristics and the relationships between cells, as well as the extracellular matrix. They are alternatives for pathophysiological or therapeutic investigation rather than animal and in vitro tests. Objective: D...

Biopsia, Técnicas de Cultivo de Célula/normas, Células Cultivadas, Expresión Génica, Luz, Melaninas/biosíntesis, Melaninas/efectos de la radiación, Organoides/efectos de la radiación, Dosis de Radiación, Reacción en Cadena en Tiempo Real de la Polimerasa, Reproducibilidad de los Resultados, Nitrato de Plata, Pigmentación de la Piel/efectos de la radiación, Factores de Tiempo, Rayos Ultravioleta

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Critical role of metabotropic glutamate receptor 4 in bone marrow-derived dendritic cells in the Th17 cell differentiation and the melanogenesis of B16 cells

Zhao, Guangming; Zhou, Wenhui; Liu, Ying; Wang, Yupeng; Li, Zhou; Song, Zhiqi.

Braz. j. med. biol. res; 53 (4), 2020

Vitiligo is an acquired pigmentary disorder resulting from selective destruction of melanocytes. Emerging studies have suggested that T helper cell 17 (Th17) is potentially implicated in vitiligo development and progression. It was recently discovered that metabotropic glutamate receptor 4 (mGluR4) can m...

Células de la Médula Ósea/citología, Diferenciación Celular/fisiología, Células Dendríticas/citología, Citometría de Flujo, Melaninas/biosíntesis, Melanocitos/citología, Ratones Endogámicos C57BL, ARN Interferente Pequeño/inmunología, Receptores de Glutamato Metabotrópico/fisiología, Células Th17/citología, Células Th17/inmunología, Vitíligo/genética, Vitíligo/inmunología

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Evaluation of melanin production by Sporothrix luriei

Cruz, Ingrid Ludmilla Rodrigues; Figueiredo-Carvalho, Maria Helena Galdino; Zancopé-Oliveira, Rosely Maria; Almeida-Paes, Rodrigo.

Mem. Inst. Oswaldo Cruz; 113 (1), 2018

There is a paucity of studies on the cell biology of Sporothrix luriei, the less common of the pathogenic Sporothrix species worldwide. The production of DHN-melanin, eumelanin, and pyomelanin were evaluated on the mycelial and yeast forms of the S. luriei ATCC 18616 strain. The mycelial form of this spe...

Melaninas/biosíntesis, Sporothrix/metabolismo

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