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The Role of MMP-9 in Regulating Degradation of the Splenic Microvascular Basement Membrane Induced by High Altitude Hypoxia

Ma, Yi; Zhu, Li-Ming; Liu, Wen-Ling; Yin, Yu-Juan; Peng, Xiao Chun; Zhu, Ming-Ming.
Int. j. morphol; 41 (4), 2023
SUMMARY: To investigate changes of MMP-9 in the rat spleen and hypoxia-induced microvascular basement membrane under high altitude hypoxia. Thirty male specific pathogen-free Sprague Dawley rats were randomly divided into control and hypoxia groups, with 15 rats in each group. The rats in the control gro...
Mal de Altura, Metaloproteinasa 9 de la Matriz, Bazo/patología, Membrana Basal/patología, Ratas Sprague-Dawley, Western Blotting, Microscopía Electrónica de Transmisión, Modelos Animales de Enfermedad
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COVID-19, glomerulonefritis ANCA y anti-membrana basal glomerular. Caso clínico

Briones, Eduardo; Méndez, Gonzalo P; Laguna, Jorge; Vargas, Miguel.
Rev. med. Chile; 150 (6), 2022
Renal involvement in COVID-19 infection is varied and worsens its outcome and prognosis. However, the association of COVID-19 infection with glomerulonephritis is exceptional. We report a 46-year-old woman with COVID-19 who had an acute kidney injury and ANCA associated glomerulonephritis two weeks after...
COVID-19/complicaciones, Glomerulonefritis/complicaciones, Anticuerpos Anticitoplasma de Neutrófilos, Autoanticuerpos, Membrana Basal/patología
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Bullous systemic lupus erythematosus in a 10-year-old child

Hans-Bittner, Nelise Ritter; Bittner, Guilherme Canho; Hans Filho, Günter; Takita, Luiz Carlos.
An. bras. dermatol; 92 (5,supl.1), 2017
Abstract: Bullous systemic lupus erythematosus (BSLE) is a rare autoimmune subepidermal blistering disease, with few cases described in childhood. It has different clinical-pathological features. We report a case of BSLE in a 10-year-old child with systemic lupus erythematosus, treated with prednisone an...
Membrana Basal/patología, Biopsia, Vesícula/tratamiento farmacológico, Vesícula/patología, Técnica del Anticuerpo Fluorescente Directa, Lupus Eritematoso Sistémico/tratamiento farmacológico, Lupus Eritematoso Sistémico/patología, Enfermedades Raras/diagnóstico por imagen, Enfermedades Raras/patología
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Linear IgA and IgG bullous dermatosis

Fernandes, Karina de Almeida Pinto; Galvis, Kely Hernández; Gomes, Anndressa Camillo da Matta Setubal; Nogueira, Osvania Maris; Felix, Paulo Antônio Oldani; Vargas, Thiago Jeunon de Sousa.
An. bras. dermatol; 91 (5,supl.1), 2016
Abstract Childhood linear immunoglobulin A dermatosis is a rare autoimmune vesiculobullous disease. It results in linear deposition of autoantibodies (immunoglobulin A) against antigens in the basal membrane zone, leading to subepidermal cleavage. Additional depositions of immunoglobulin G and complement...
Dermatosis Bullosa IgA Lineal/patología, Piel/patología, Membrana Basal/patología, Biopsia, Eritema/patología, Técnica del Anticuerpo Fluorescente Directa, Enfermedades Cutáneas Vesiculoampollosas/patología
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