LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Vitamin D3 mediates spatial memory improvement through nitric oxide mechanism in demyelinated hippocampus of rat

Ataie, Zahra; Choopani, Samira; Foolad, Forough; Khodagholi, Fariba; Goudarzvand, Mahdi.

Braz. J. Pharm. Sci. (Online); 58 (), 2022

Abstract Studies have revealed beneficial role of vitamin D3 in neuro-cognitive function. There is also supporting evidence on the involvement of nitric oxide (NO) in the neuro-protective action. However, its over production could contribute to brain disorders. In this study, demyelination was induced by...

Colecalciferol/análisis, Óxido Nítrico/efectos adversos, Memoria Espacial/clasificación, Etidio/efectos adversos, Prueba del Laberinto Acuático de Morris, Enfermedades Desmielinizantes/clasificación, Encefalopatías/patología

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The effects of acute administration of the hydroalcoholic extract of rosemary (Rosmarinus officinalis L. ) (Lamiaceae) in animal models of memory

Rosmarinus officinalis (Rosemary) demonstrates antioxidant, antidepressant, diuretic, antinociceptive and antiulcerogenic activities. The present study was designed to examine the effects of the hydroalcoholic extract of R. officinalis on the memory of male mice. The behavioral tasks employed were social...