1-triacontanol cerotate isolated from Marsilea quadrifolia Linn. safeguards hippocampal CA3 neurons and augments special memory deficit in chronic epileptic rats
Int. j. morphol; 37 (1), 2019
SUMMARY: Currently many people with epilepsy do not have seizure control even with the best available medications. Moreover various antiepileptics have adverse cognitive impact with other side effect. Thus, need for new antiepileptic drugs still remains challenge. However, many of the natural components ...
Epilepsia/tratamiento farmacológico, Marsileaceae/química, Enfermedad Crónica, Alcoholes Grasos/administración & dosificación, Ácidos Grasos, Hipocampo/efectos de los fármacos, Memoria Espacial/efectos de los fármacos, Región CA3 Hipocampal/efectos de los fármacos, Ratas Wistar, Pentilenotetrazol/efectos adversos, Alcoholes Grasos/aislamiento & purificación, Epilepsia/inducido químicamente, Células Piramidales, Prueba del Laberinto Acuático de Morris