LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Sex-differential effects of olanzapine vs. aripiprazole on glucose and lipid metabolism in first-episode schizophrenia

ZHOU, XUE-MEI; HU, MAO-RONG; GONG, MEI-YU; ZOU, XUE-LIANG; YU, ZHI-MIN.

Arch. Clin. Psychiatry (Impr.); 46 (2), 2019

Abstract Objective To compare sex difference in metabolic effect of olanzapine versus aripiprazole on schizophrenia. Methods A twelve-week prospective open-label cohort study to compare four subgroups according to first-episode schizophrenia patients' type of drug usage and sex: female aripiprazole (...

Esquizofrenia/tratamiento farmacológico, Glucemia/efectos de los fármacos, Metabolismo de los Lípidos/efectos de los fármacos, Factores Sexuales, Aumento de Peso/efectos de los fármacos, Índice de Masa Corporal, Olanzapina/efectos adversos, Aripiprazol/efectos adversos, Estudios Prospectivos, Triglicéridos/sangre, Lipoproteínas LDL/sangre, Lipoproteínas HDL/sangre

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Palmitic acid-induced lipotoxicity promotes a novel interplay between Akt-mTOR, IRS-1, and FFAR1 signaling in pancreatic β-cells

Marafie, Sulaiman K; Al-Shawaf, Eman M; Abubaker, Jehad; Arefanian, Hossein.

Biol. Res; 52 (), 2019

BACKGROUND: Free fatty acid receptor 1 (FFAR1) is G-protein coupled receptor predominantly expressed in pancreatic β-cells that is activated by a variety of free fatty acids (FFAs). Once activated, it promotes glucose-stimulated insulin secretion (GSIS). However, increased levels of FFAs lead to lipotox...

Células Secretoras de Insulina/efectos de los fármacos, Metabolismo de los Lípidos/efectos de los fármacos, Ácido Palmítico/toxicidad, Proteínas Proto-Oncogénicas c-akt/metabolismo, Serina-Treonina Quinasas TOR/metabolismo, Receptores Acoplados a Proteínas G/metabolismo, Células Secretoras de Insulina/metabolismo, Apoptosis, Línea Celular, Transducción de Señal

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Efectos adversos de finasteride: mitos y realidades. una revisión actualizada

Carreño-Orellana, Néstor; Moll-Manzur, Catherina; Carrasco-Zuber, Juan Eduardo; Álvarez-Véliz, Sergio; Berroeta-Mauriziano, Daniela; Porras-Kusmanic, Ninoska.

Rev. méd. Chile; 144 (12), 2016

Finasteride is a 5-α reductase inhibitor that is widely used in the management of benign prostate hyperplasia and male pattern hair loss. It is well known that these agents improve the quality of life in men suffering from these conditions. However, they are associated with some transient and even p...

Finasterida/efectos adversos, Inhibidores de 5-alfa-Reductasa/efectos adversos, Inhibidores de 5-alfa-Reductasa/uso terapéutico, Alopecia/tratamiento farmacológico, Glucemia/metabolismo, Disfunción Eréctil/inducido químicamente, Finasterida/uso terapéutico, Metabolismo de los Lípidos/efectos de los fármacos, Hiperplasia Prostática/tratamiento farmacológico, Neoplasias de la Próstata/prevención & control, Espermatogénesis/efectos de los fármacos

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Impact of vigorous exercise on serum levels of L-Carnitine in prisoners in Colombia

Acevedo-Pabón, Ángel F; Manrique-Abril, Fred G; Ospina-Díaz, Juan M.

Rev. salud pública; 17 (5), 2015

Objective To assess the effect of a program of vigorous physical exercises on the serum concentration of free and total L-carnitine, in male inmates at a prison in Boyacá, Colombia. Methods Pre-post intervention population-based study. 44 male prisoners with overweight and/or obesity, from a jail in Boy...

Obesidad/fisiopatología, Metabolismo de los Lípidos/efectos de los fármacos, Carnitina/administración & dosificación, Ejercicio Físico, Prisioneros, Colombia

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