Glioblastomas (GBM) são conhecidos como os tumores mais comuns e letais que se desenvolvem no sistema nervoso central. Eles são considerados os gliomas difusos mais agressivos e que possuem alta resistência a tratamentos de radioterapia e quimioterapia, além de serem um dos tumores mais vascularizado...
Snake venoms are composed of pharmacologically active proteins that are evolutionarily diverse, stable and specific to targets. Hence, venoms have been explored as a source of bioactive molecules in treating numerous diseases. Recent evidences suggest that snake venom proteins may affect the formation of...
ABSTRACT Purpose Quantify the tissue content of metalloproteinase-9 (MMP-9) and collagen in colic mucosa with and without intestinal transit after infliximab administration in rats subjected to Hartmann's surgery. Methods Twenty-two rats underwent colon diversion by Hartmann's surgery. Animals were mai...
OBJECTIVES: Arterial embolization of myomas (AEM) is controversial because of the changes that occur in the extracellular matrix (ECM) of the endometrium and its effect on gestational success in infertile patients desiring reproductive capability. Therefore, we performed this study on the expression of g...
Pereira, Leandro de Mattos;
Messias, Elisa Alves;
Sorroche, Bruna Pereira;
Oliveira, Angela das Neves;
Arantes, Lidia Maria Rebolho Batista;
Carvalho, Ana Carolina de;
Tanaka-Azevedo, Anita Mitico;
Grego, Kathleen Fernandes;
Carvalho, André Lopes;
Melendez, Matias Eliseo.
Lack of complete genomic data of Bothrops jararaca impedes molecular biology research focusing on biotechnological applications of venom gland components. Identification of full-length coding regions of genes is crucial for the correct molecular cloning design. Methods: RNA was extracted from the venom ...
Abstract 18. Introduction: Tooth development results from a highly coordinated epithelial-mesenchyme interaction in which mesenchyme cells originate the dental papilla and dental follicle, while ectodermal cells originate the enamel organ. Simultaneously, bone tissue is formed around the developing too...
Tityus serrulatus venom (Ts venom) is a complex mixture of several compounds with biotechnological and therapeutical potentials, which highlights the importance of the identification and characterization of these components. Although a considerable number of studies have been dedicated to the characteriz...
Canello, V. A;
Gravena, K;
Tovar, M. C. H;
Dias, D. P. M;
Gomide, L. M. W;
Bernardi, N. S;
Sabes, A. F;
Queiroz, D. J;
Melo, G. D;
Machado, G. F;
Lacerda Neto, J. C.
O objetivo deste estudo foi avaliar a expressão das MMP-2 e MMP-9 no tecido laminar do casco e o perfil leucocitário de equinos submetidos à obstrução intraluminal do cólon menor. Realizaram-se laparotomia e obstrução do cólon menor de oito equinos hígidos, utilizando-se uma bola inserida no l�...
Animal poisons and venoms are sources of biomolecules naturally selected. Rhinella schneideri toads are widespread in the whole Brazilian territory and they have poison glands and mucous gland. Recently, protein from toads’ secretion has gaining attention. Frog skin is widely known to present great num...
Lachesis muta rhombeata (Lmr) is the largest venomous snake in Latin America and its venom contains mainly enzymatic components, such as serine and metalloproteases, L-amino acid oxidase and phospholipases A2. Metalloproteases comprise a large group of zinc-dependent proteases that cleave basement membra...
