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Clinical attachment loss and molecular profile of inflamed sites before treatment

Borges, Cristine D Almeida; Ricoldi, Milla Sprone; Messora, Michel Reis; Palioto, Daniela Bazan; Souza, Sérgio Luís Scombatti de; Novaes Júnior, Arthur Belém; Taba Jr, Mario.
J. appl. oral sci; 27 (), 2019
Abstract Objective: To monitor early periodontal disease progression and to investigate clinical and molecular profile of inflamed sites by means of crevicular fluid and gingival biopsy analysis. Methodology: Eighty-one samples of twenty-seven periodontitis subjects and periodontally healthy individual...
Biomarcadores/análisis, Biopsia, Estudios de Casos y Controles, Citocinas/análisis, Encía/patología, Líquido del Surco Gingival/química, Metaloproteinasa 8 de la Matriz/análisis, Osteoprotegerina/análisis, Pérdida de la Inserción Periodontal/patología, Periodontitis/terapia, Reacción en Cadena en Tiempo Real de la Polimerasa, Saliva/química, Estadísticas no Paramétricas, Factores de Tiempo, Factor A de Crecimiento Endotelial Vascular/análisis
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Local application of statins in the treatment of experimental periodontal disease in rats

SANTOS, Bianca Fernanda Espósito; SOUZA, Eduardo Quintão Manhanini; BRIGAGÃO, Maísa Ribeiro Pereira Lima; LIMA, Daniela Coelho de; FERNANDES, Leandro Araújo.
J. appl. oral sci; 25 (2), 2017
Abstract Objective The objective of this study was to evaluate the local effects of statins as adjuvants for treatment by scaling and root planing (SRP) of periodontal disease induced in rats. Material and Methods Ninety rats were used in the present experiment. Periodontal disease was induced in all...
Biopsia, Conservadores de la Densidad Ósea/farmacología, Quimioterapia Adyuvante, Encía/efectos de los fármacos, Encía/patología, Mandíbula/diagnóstico por imagen, Mandíbula/patología, Metaloproteinasa 8 de la Matriz/análisis, Periodontitis/tratamiento farmacológico, Periodontitis/patología, Ratas Wistar, Reproducibilidad de los Resultados, Aplanamiento de la Raíz/métodos, Simvastatina/farmacología, Factores de Tiempo
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Cytokine and metalloproteinases in gingival fluid from patients with chronic periodontitis

Escalona, Laura A; Mastromatteo-Alberga, Patrizzia; Correnti, María.
Invest. clín; 57 (2), 2016
The purpose of the present research was to determine the levels of IL-1α, IL-1β, TNF-α, IL-6, IL-6sR, IL-8, IL-10, MMP-3 and MMP-8 in gingival crevicular fluid (GCF) of subjects with chronic periodontitis. Clinical measurements were carried out in 20 patients with chronic periodontitis and...
Periodontitis Crónica/metabolismo, Citocinas/análisis, Líquido del Surco Gingival/química, Metaloproteinasa 3 de la Matriz/análisis, Metaloproteinasa 8 de la Matriz/análisis
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