Results: 8

Polymorphisms of matrix metalloproteinase-7 and -9 are associated with oral tongue squamous cell carcinoma

Abstract Matrix degradation is an important event in the progression, invasion and metastasis of malignant head and neck lesions. Imbalances, mutations and polymorphisms of MMPs and their inhibitors are observed in several cancer subtypes. The aim of this study was to evaluate the association of the MMP-...

Association between matrix metalloproteinase-9 gene polymorphism and breast cancer in Brazilian women

Clinics; 75 (), 2020
OBJECTIVE: This study aimed to determine the relationship between rs17576 (MMP-9) polymorphism and increased cancer risk in a Brazilian breast cancer cohort. METHODS: This study included 141 women (71 breast cancer patients and 70 controls without breast cancer) who donated 3 mL of their peripheral bloo...

Is the expression of the components of the carotid matrix of rats influenced by estrogen, progestin and tibolone?

Abstract Objective To analyze the effects of estrogen alone or in combination with progestogens and tibolone (TIB) on the expression of the extracellular matrix metalloproteinases 2 and 9 (MMP-2 and MMP-9), of perlecan, and of heparanase (HPSE) of the vascular walls of the carotid arteries. Methods A...

Assessment of metalloproteinase matrix 9 (MMP9) gene polymorphisms risk factors for pelvic organ prolapse in the brazilian population

Abstract Objective To evaluate the C-1562T matrix metalloproteinase 9 (MMP9) gene polymorphisms as risk factors related to the occurrence of pelvic organ prolapse (POP) and to identifytheclinicalvariablesassociatedwith theoccurrenceof thedisease.Epidemiological studies of risk factors for POP do not ex...

Association between matrix metallopeptidase 9 polymorphism and breast cancer risk

Abstract Objective Epidemiological studies have shown evidence of the effect of genetic variations in the pathogenesis of breast cancer and have suggested a relationship of the disease with genetic polymorphisms. Matrix metallopeptidase 9 (MMP-9) is a collagenase responsible for the degradation of type...

Polymorphisms in chronic rhinosinusitis with nasal polyps - a systematic review

Abstract Introduction: Chronic rhinosinusitis with nasal polyps is a multifactorial disease with a complex pathophysiology involving multiple genetic and environmental factors. Objective: The purpose of this work review is to focus on the importance of genetic studies in chronic rhinosinusitis with nas...

Genetic Polymorphism in MMP9 May Be Associated With Anterior Open Bite in Children

Braz. dent. j; 28 (3), 2017
Abstract Anterior open bite (AOB) has a multifactorial etiology caused by the interaction of sucking habits and genetic factors. The aim of this study was to evaluate the association between AOB and polymorphisms in genes that encode Matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs). F...

Expressão das metaloproteinases 2 e 9 em adenocarcinoma colorretal

Rev. AMRIGS; 52 (4), 2008
Introdução: Os carcinomas da região colorretal representam o terceiro tipo mais comum de neoplasia maligna e a terceira causa de mortalidade relacionada ao câncer no mundo. Objetivos: Este estudo teve como objetivo verificar se existe associação entre estadiamento, invasão vascular, tamanho do tum...