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Possible therapeutics for Pseudomyxoma peritonei: a rare, lethal, and the least investigated disease

Nazmeen, Aarifa.
J. coloproctol. (Rio J., Impr.); 43 (2), 2023
Pseudomyxoma peritonei (PMP) refers to a growth disorder characterized by glycoprotein neoplasm in the peritoneum, where mucin oversecretion occurs. The tumors of the appendix region are well associated with PMP; however, ovarian, colon, stomach, pancreas, and urachus tumors have also been linked to PMP....
Seudomixoma Peritoneal/tratamiento farmacológico, Aporfinas/uso terapéutico, Amilorida/uso terapéutico, Dexametasona/uso terapéutico, Naltrexona/uso terapéutico, Retinoides/uso terapéutico, Metilación/efectos de los fármacos, Mucinas/efectos de los fármacos, Calcio
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Methylation of p16 ink4a promoter is independent of human papillomavirus DNA physical state: a comparison between cervical pre-neoplastic and neoplastic samples

Carestiato, Fernanda Nahoum; Amaro-Filho, Sergio Menezes; Moreira, Miguel Angelo Martins; Cavalcanti, Silvia Maria Baeta.
Mem. Inst. Oswaldo Cruz; 114 (), 2019
BACKGROUND Epigenetic modifications in host cells, like p16 ink4a methylation, have been considered as putative complementary mechanisms for cancer development. Because only a small proportion of infected women develop cervical cancer, other factors might be involved in carcinogenesis, either independen...
Papillomaviridae/fisiología, Neoplasias del Cuello Uterino/prevención & control, Inhibidor p16 de la Quinasa Dependiente de Ciclina, Metilación/efectos de los fármacos, Factores de Integración del Huésped/uso terapéutico
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