Results: 3

Effects of DACT1 methylation status on invasion and metastasis of nasopharyngeal carcinoma

Biol. Res; 52 (), 2019
BACKGROUND: The purpose of the present study was to investigate the role of the methylation status of the DACT1 gene on the invasion and metastasis of nasopharyngeal carcinoma cells. METHODS: The levels of methylation and expression of the DACT1 gene in nasopharyngeal carcinoma tissues and CNE2 cells wer...

Methylation profile of the ADRB3 gene and its association with lipid profile and nutritional status in adults

Biol. Res; 52 (), 2019
BACKGROUND: Defects in DNA methylation have been shown to be associated with metabolic diseases such as obesity, dyslipidemia, and hypercholesterolemia. To analyze the methylation profile of the ADRB3 gene and correlate it with lipid profile, lipid intake, and oxidative stress based on malondialdehyde (M...

A influência de polimorfismos de base única na metilação de DNA em genes de receptores olfatórios

Os genes de receptores olfatórios (OR) pertencem a uma família de proteínas de membrana formada por cerca de 1000 genes no genoma de camundongo. Os genes OR são expressos de forma monogênica e monoalélica nos neurônios olfatórios (OSNs). No entanto, ainda não está claro o mecanismo que permite ...