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Immature rat testis sustained long-term development using an integrative model

Ma, Yubo; Chen, Juan; Li, Hecheng; Xu, Fangshi; Chong, Tie; Wang, Ziming; Zhang, Liandong.
Biol. Res; 55 (), 2022
BACKGROUND: Xenotransplantation has been primarily performed using fresh donor tissue to study testicular development for about 20 years, and whether the cultured tissue would be a suitable donor is unclear. In this study, we combined testicular culture and xenotransplantation into an integrative model a...
Acrosina/metabolismo, Antioxidantes/metabolismo, Proteína 1 Asociada A ECH Tipo Kelch/metabolismo, Metiltransferasas/metabolismo, Factor 2 Relacionado con NF-E2/metabolismo, Espermatogénesis, Superóxido Dismutasa-1/metabolismo, Testículo/metabolismo
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Spatio-temporal expression profile of Mettl3/Mettl14 during mouse retina development

Zhong, Qi; Guo, Jingyi; Chen, Shuyi.
Int. j. morphol; 38 (6), 2020
SUMMARY: The Mettl3/Mettl14 methyltransferase complex installs the most ubiquitous internal mRNA modification- N6-methyladenosine (m6A). The vertebrate retina development is a multi-step process that requires fine-tuning of multiple cellular events, but very little is known about the potential function o...
Retina/embriología, Retina/enzimología, Metiltransferasas/metabolismo, Metiltransferasas/genética, Reacción en Cadena en Tiempo Real de la Polimerasa, Inmunohistoquímica, Ratones Endogámicos C57BL, Coloración y Etiquetado
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