Results: 26

Avaliação da qualidade de vida em pacientes com malignidades hematológicas
Assessment of quality of life in patients with hematological malignancies

As malignidades hematológicas formam um grupo heterogêneo de cânceres que afetam o sangue, a medula óssea e o sistema linfático. Objetivo: Avaliar a qualidade de vida relacionada à saúde em um grupo de pacientes com malignidades hematológicas. Método: Estudo transversal analítico com abordagem...

Aportes de la tomografía por emisión de positrones con 18F-fluorodesoxiglucosa/tomografía computada en el diagnóstico de compromiso extramedular por mieloma múltiple en Uruguay

Rev. méd. Chile; 150 (2), 2022
BACKGROUND: 18F-fluorodesoxyglucose positron emission tomography/ computed tomography (PET-CT) has a high sensitivity and specificity to detect medullary and extramedullary lesions in multiple myeloma (MM). AIM: To describe the findings of PET-CT in extramedullary multiple myeloma (EMM) at diagnosis and ...

Impact of quality of response on survival outcomes among multiple myeloma patients treated with novel agents - a retrospective analysis

Säo Paulo med. j; 140 (2), 2022
Abstract BACKGROUND: In this era of target therapies, novel data on the correlation between response endpoints and survival outcomes in multiple myeloma have arisen. OBJECTIVE: To determine the impact of quality of response on clinical outcomes, using first-line treatment, and identify risk factors inf...

Cross-cultural translation and adaptation of Functional Assessment of Cancer Therapy - Multiple Myeloma tool - MM1 and LEU3 - for Portuguese

ABSTRACT Objective To describe of the translation from English to Portuguese and adaption process of subitems of the Functional Assessment of Cancer Therapy - Multiple Myeloma. Methods In the first phase, translations from English into Portuguese of two subitems of Functional Assessment of Cancer The...

Prospective identification of potential factors influencing stem cell mobilization and the necessity for plerixafor use in newly diagnosed multiple myeloma patients undergoing autologous stem cell transplantation

ABSTRACT Introduction: To study the efficacy and safety of single large volume leukapheresis by using generic G-CSF or G-CSF plus Plerixafor in achieving adequate stem cell yield and various factors influencing thereof in newly diagnosed multiple myeloma patients undergoing autologous stem cell transpla...

Results of the daratumumab monotherapy early access treatment protocol in patients from Brazil with relapsed or refractory multiple myeloma

ABSTRACT Introduction: Daratumumab is a CD38-targeting monoclonal antibody with established efficacy and safety in patients with relapsed or refractory multiple myeloma (RRMM). We report results of an early access protocol (EAP) of daratumumab monotherapy for RRMM in a cohort of Brazilian patients. Met...

Cyclophosphamide-glucocorticoids versus lenalidomide-dexamethasone as treatment for multiple myeloma at first relapse after autologous stem cell transplantation - a retrospective analysis

ABSTRACT There have been significant improvements in therapeutic options for relapsed multiple myeloma (MM) over the past two decades, with many novel agents including proteasome inhibitors, immunomodulatory agents, and more recently monoclonal antibodies demonstrating efficacy in this setting. However, ...

Encefalite herpética associada a mieloma múltiplo: desafio diagnóstico

O mieloma múltiplo é a segunda neoplasia onco-hematológica mais comum, correspondendo a 1% das neoplasias malignas. Trata-se de uma condição subdiagnosticada, assim como a encefalite herpética. Entretanto, é comum a relação do mieloma com infecções, em decorrência do acometimento da imunidade...

Síndrome de hiperviscosidade em paciente com mieloma múltiplo

O mieloma múltiplo é uma neoplasia progressiva e incurável de células B, caracterizado pela proliferação desregulada e clonal de plasmócitos na medula óssea. A síndrome de hiperviscosidade é uma das complicações relacionadas às gamopatias monoclonais, sendo considerada emergência oncol�...

Artritis séptica de la rodilla como forma de presentación de mieloma múltiple
Septic Arthritis of the Knee as a Presentation of Multiple Myeloma

RESUMEN Introducción: El mieloma múltiple constituye una proliferación maligna de las células plasmáticas derivadas de un solo clon. El tumor, sus productos y la respuesta del paciente ocasionan diversos trastornos funcionales orgánicos y síntomas como dolores óseos o fracturas, insuficiencia r...