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Hepatic mitochondria in diet-induced obese mice (stereology and molecular analysis)

Reis-Barbosa, Pedro Henrique; Carvalho, Jorge Jose de; Sol, Mariano del; Mandarim-de-Lacerda, Carlos Alberto.
Int. j. morphol; 39 (2), 2021
SUMMARY: The world population is going through an obesity epidemic that has severe consequences for the health system. This study focused on studying hepatic mitochondria in obese animals induced by a high-fat (HF) diet and used the model-based stereology in electron micrographs for the quantitative stud...
Obesidad/metabolismo, Dieta Alta en Grasa, Hígado/metabolismo, Mitocondrias Hepáticas/metabolismo, Ratones Endogámicos C57BL, Reacción en Cadena en Tiempo Real de la Polimerasa, Aumento de Peso, Mitocondrias Hepáticas/ultraestructura, Mitocondrias Hepáticas/genética, Marcadores Genéticos, Biogénesis de Organelos
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Physical training reverses changes in hepatic mitochondrial diameter of Alloxan-induced diabetic rats

Kuga, Gabriel Keine; Gaspar, Rafael Calais; Muñoz, Vitor Rosetto; Nakandakari, Susana Castelo Branco Ramos; Breda, Leonardo; Sandoval, Bruna Marina; Caetano, Flávio Henrique; Leme, José Alexandre Curiacos de Almeida; Pauli, José Rodrigo; Gomes, Ricardo José.
Einstein (Säo Paulo); 16 (3), 2018
ABSTRACT Objective To investigate the effects of physical training on metabolic and morphological parameters of diabetic rats. Methods Wistar rats were randomized into four groups: sedentary control, trained control, sedentary diabetic and trained diabetic. Diabetes mellitus was induced by Alloxan (3...
Glucemia/metabolismo, Peso Corporal, Diabetes Mellitus Experimental/inducido químicamente, Diabetes Mellitus Experimental/metabolismo, Prueba de Esfuerzo, Insulina, Factor I del Crecimiento Similar a la Insulina/metabolismo, Hígado/anatomía & histología, Hígado/metabolismo, Hígado/ultraestructura, Glucógeno Hepático/metabolismo, Mitocondrias Hepáticas/ultraestructura, Condicionamiento Físico Animal/fisiología, Distribución Aleatoria, Ratas Wistar, Natación/fisiología
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