Results: 12

Establishment of deer heart identification method and development of the detection kit based on mitochondrial cytochrome B gene

BACKGROUND Deer heart is a valuable traditional Chinese medicinal material. At present, there is no functional component or symbol component for deer heart, and it is difficult to identify them by physical and chemical methods. In this study, we established deer heart identification method based on mtDNA...

Oxygen use in Atacama large millimeter and submillimeter (ALMA) arrays in Chajnantor valley at 5050 m

The Chilean workforce has over 200,000 people that are intermittently exposed to altitudes over 4000 m. In 2012, the Ministry of Health provided a technical guide for high altitude workers that included a series of actions to mitigate the effects of hypoxia. Previous studies have shown the positive effec...

A new gene inventory of the ubiquitin and ubiquitin-like conjugation pathways in Giardia intestinalis

Mem. Inst. Oswaldo Cruz; 115 (), 2020
BACKGROUND Ubiquitin (Ub) and Ub-like proteins (Ub-L) are critical regulators of complex cellular processes such as the cell cycle, DNA repair, transcription, chromatin remodeling, signal translation, and protein degradation. Giardia intestinalis possesses an experimentally proven Ub-conjugation system;...

The usefulness of Tanita TBF-310 for body composition assessment in Judo athletes using a four-compartment molecular model as the reference method

SUMMARY Body composition assessment at the molecular level is relevant for the athletic population and its association with high performance is well recognized. The four-compartment molecular model (4C) is the reference method for fat mass (FM) and fat-free mass (FFM) estimation. However, its implementat...

High and ultra low concentrations of Mercuric chloride initiate their specific action on binding sites of invertase and modify its interaction with sucrose

Int. j. high dilution res; 18 (3/4), 2019
Background: Mercuric chloride is known to inhibit the activity of enzymes. It is used in homeopathy at ultra low concentration (ULC) and is known as Mercurius corrosivus (Merc cor). ULCs of Merc cor are reported to promote enzyme activity. Objective: To see whether the mother tincture (θ) of Merc cor an...

Estructura molecular de los ácidos nucleicos. Una estructura para el Ácido Desoxirribonucleico
The molecular structure of nucleic acids. An structure for Desoxirribonucleic acid

Deseamos sugerir una estructura para la sal del Ácido Desoxirribonucleico (A.D.N.). Esta estructura tiene aspectos novedosos que son de un interés biológico considerable. Una estructura para el ácido nucleico ya ha sido propuesta por Pauling y Corey:1 Amablemente han puesto el manuscrito a nuestra d...

Structure analysis of capsid protein of Porcine circovirus type 2 from pigs with systemic disease

Braz. j. microbiol; 49 (2), 2018
Abstract Economic losses with high mortality rate associated with Porcine circovirus type 2 (PCV2) is reported worldwide. PCV2 commercial vaccine was introduced in 2006 in U.S. and in 2008 in Brazil. Although PCV2 vaccines have been widely used, cases of PCV2 systemic disease have been reported in the la...

Structural insights into leishmanolysins encoded on chromosome 10 of Leishmania (Viannia) braziliensis

Mem. Inst. Oswaldo Cruz; 112 (9), 2017
BACKGROUND Leishmanolysins have been described as important parasite virulence factors because of their roles in the infection of promastigotes and resistance to host's defenses. Leishmania (Viannia) braziliensis contains several leishmanolysin genes in its genome, especially in chromosome 10. However, ...

Peptídeos de conformação restrita relacionados ao sítio 2 do fator de crescimento de fibroblastos ácido humano (hFGF-1): estudo sobre estrutura e atividade

Na busca por agonistas, antagonistas e inibidores de natureza peptídica do fator de crescimento de fibroblastos ácido humano (hFGF-1), iniciamos o presente trabalho fazendo uma análise conformacional teórica do peptídeo Ac-WFVGLKKNGSSKRGPRT-N`H IND. 2ï (107-123[hFGF-1]). Em trabalho anterior, este ...