LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud | LILACS

Results: 3

Terapia com células CAR-T: reprogramação celular para o combate de neoplasias malignas

As células CAR-T são linfócitos geneticamente modificados para reconhecerem um espectro amplo de antígenos de superfície celulares. Além disso, atacam células tumorais malignas, que expressam esses antígenos, por meio da ativação da coestimulação citoplasmática, secreção de citocinas, citÃ...

Frequency of Variants in DNA-Repair Genes in a Southwest Colombian Population

Objective To describe the frequency of mutations in DNA-repair genes in a southwestern Colombian population. Methods We have designed an observational study, including 162 people from all ages from southwest Colombia. We have extracted and collected their DNA in filters. We have immersed the DNA in a...

Cancer Stem Cells are Depolarized Relative to Normal Stem Cells Derived from Human Livers

Ann. hepatol; 16 (2), 2017
ABSTRACT Introduction and aim. The inability to distinguish cancer (CSCs) from normal stem cells (NSCs) has hindered attempts to identify safer, more effective therapies for hepatocellular carcinoma (HCC). The aim of this study was to document and compare cell membrane potential differences (PDs) of CS...