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Morphine promotes migration and lung metastasis of mouse melanoma cells

Braz. J. Anesth. (Impr.); 73 (4), 2023
Abstract Background Morphine is an analgesic agent used for cancer pain management. There have been recent concerns that the immunosuppressant properties of morphine can also promote cancer metastasis. Morphine is an agonist for toll like receptor 4 (TLR4) that has a dual role in cancer development. The...