Obesity is a very common pathology worldwide. Among the management alternatives are glucagon-like peptide-1
(GLP-1) analogues, a hormone secreted mainly by the intestine. Apart from its effects as an incretin, effects on
gastrointestinal motility have been described, which seem to be fundamental for its ...
SUMMARY: Cadmium (Cd) is the industrial and environmental toxic heavy metal which is found in air, water and soil. Cd, adversely affects many organs in humans such as kidney, intestine, liver, testis and lungs. L-carnitine (LC) is an important agent that plays essential role in energy metabolism. In our ...
SUMMARY: Ischemia-reperfusion (I/R) of the small intestine causes serious abdominal pathologies including tissue dysfunction and organ failure. L-carnitine (L-C), a powerful antioxidant, may help lessen the severity of these pathological effects since it plays a key role in energy metabolism. In this wor...
Abstract Purpose To investigate the effect of probiotics on spontaneous contractions of smooth muscle isolated from jejunum and ileum of rat model. Methods Four rat groups were created (n=8, in each) including control (Group 1), control+probiotic (Group 2), short bowel (Group 3), and short bowel+probio...
La cisaprida es hasta hoy el procinético intestinal de mayor uso en el mundo para el tratamiento de los trastornos de motilidad gastrointestinal, en México disponible de 1987 a la fecha, la farmacocinética y farmacodinámica han cobrado inusitada importancia al reportarse efectos adversos cardiacos po...
La eritromicina, un antibiótico del grupo de los macrólidos, ha demostrado recientemente que tiene un efecto similar a la motilina sobre la fibra muscular gastrointestinal. Mostramos nuestra experiencia en 4 casos de tratamiento exitoso de la gastroparesia postoperatoria con eritromicina oral. Todos er...
Cada segmento do tubo digestivo tem um padräo próprio de motilidade e toda atividade motora resulta fundamentalmente das propriedades elétricas do músculo liso. Em sua atividade motora, o duodeno apresenta funçöes de mistura e progressäo, como também participa do controle do esvaziamento gástric...
A ausência de sais biliares na luz intestinal de pacientes com obstruçao biliar tem sido relacionada ao aumento da flora intestinal e maior produçao de endotoxinas, podendo provocar endotoxemia sistêmica. Entretanto, esses sais têm pequena açao sobre a flora aeróbia e facultativa, que pode estar a...
Coleus barbatus (Labiatae) Benth is popularly used in Brazil "for the healing of liver and stomach diseases". The water extract (WE 1 to 10 g/Kg, p.o.) of stem and leaves given to rats and mice did not induce signs of intoxication. Preveious treatment of mice with WE (1 g/kg, p.o.) shortened the sleeping...
