The impact of laronidase treatment in otolaryngological manifestations of patients with mucopolysaccharidosis
Braz. j. otorhinolaryngol. (Impr.); 82 (5), 2016
ABSTRACT INTRODUCTION: Mucopolysaccharidosis (MPS) is a lysosomal storage disease caused by deficiency of a-l-iduronidase. The otolaryngological findings include hearing loss, otorrhea, recurrent otitis, hypertrophy of tonsils and adenoid, recurrent rhinosinusitis, speech disorders, snoring, oral breath...