LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Drogas imunossupressoras afetam os núcleos hipotalâmicos envolvidos na ingestão alimentar ? estudo experimental

Schuh, Rodrigo; Veronez, Djanira Aparecida da Luz; Ramos, Eduardo José Brommelstroet; Cunha, Flávia Dorieux Wastner; Pereira, Mattheus Lopes; Aranha, Jeferson de Jesus; Aranha, Marcelo Alves; Matias, Jorge Eduardo Fouto.

ABCD (São Paulo, Impr.); 34 (4), 2021

RESUMO - RACIONAL: Drogas imunossupressoras são indispensáveis para pacientes pós-transplante, diminuindo, significativamente, os riscos de rejeição inerentes a este tipo de procedimento. No entanto, seus efeitos colaterais sobre os núcleos hipotalâmicos envolvidos na regulação da ingestão de a...

Núcleo Arqueado del Hipotálamo, Ingestión de Alimentos, Hipotálamo, Preparaciones Farmacéuticas, Ratas Wistar

Fulltext

Repeated binge-like ethanol administration during adolescence cause decreased C-Fos immunoreactivity in amygdala and arcuate nucleus in adult Sprague-Dawley rats

Lerma-Cabrera, Jose Manuel; Carvajal, Francisca; Alcaraz-Iborra, Manuel; Sanchez-Amate, Maria del Carmen; de la Fuente, Leticia; Cubero, Inmaculada.

Int. j. morphol; 32 (2), 2014

Binge alcohol drinking during adolescence has been associated with neurotoxicity and increased risk for the development of alcohol use disorders. There is evidence that acute and chronic ethanol administration alters c-fos expression, an indirect index of cellular activity, in different brain regions in ...

Etanol/administración & dosificación, Etanol/farmacología, Proteínas Proto-Oncogénicas c-fos/efectos de los fármacos, Núcleo Arqueado del Hipotálamo/efectos de los fármacos, Núcleo Amigdalino Central/efectos de los fármacos, Núcleo Hipotalámico Paraventricular/efectos de los fármacos, Inmunohistoquímica, Factores de Edad

Fulltext

A single high dose of chlorpyrifos reduces long-term basal c-fos expression in the rat arcuate hypothalamic nucleus

Carvajal, F; Lerma-Cabrera, J M; Sánchez-Amate, M C; Cubero, I.

Int. j. morphol; 32 (1), 2014

Chlorpyrifos (CPF) is an organophosphate compound used worldwide as a pesticide in agriculture that, after subcutaneous injection, keeps acetylcholinesterase (AChE) activity inhibited within an organism for months. Ample clinical and experimental evidence shows that CPF exposure induces relevant and pers...

Cloropirifos/administración & dosificación, Insecticidas Organofosforados, Núcleo Arqueado del Hipotálamo/efectos de los fármacos, Proteínas Proto-Oncogénicas c-fos/efectos de los fármacos, Etanol, Inyecciones, Ratas Wistar

Fulltext