Results: 2

Nitric oxide modulates ATP-evoked currents in mouse Leydig cells

de Deus, JL; Dagostin, ALA; Varanda, WA.

Braz. j. med. biol. res; 51 (5), 2018

Testosterone synthesis within Leydig cells is a calcium-dependent process. Intracellular calcium levels are regulated by different processes including ATP-activated P2X purinergic receptors, T-type Ca2+ channels modulated by the luteinizing hormone, and intracellular calcium storages recruited by a calci...

Potenciales de Acción, Adenosina Trifosfato/fisiología, Arginina/administración & dosificación, Arginina/metabolismo, Células Cultivadas, GMP Cíclico/administración & dosificación, GMP Cíclico/análogos & derivados, GMP Cíclico/metabolismo, Células Intersticiales del Testículo/fisiología, NG-Nitroarginina Metil Éster/administración & dosificación, NG-Nitroarginina Metil Éster/metabolismo, Óxido Nítrico/biosíntesis, Óxido Nítrico/fisiología, Técnicas de Placa-Clamp, Receptores Purinérgicos/metabolismo, Tionucleótidos/administración & dosificación, Tionucleótidos/metabolismo

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Aerobic Swim Training Restores Aortic Endothelial Function by Decreasing Superoxide Levels in Spontaneously Hypertensive Rats

Jordão, Camila P; Fernandes, Tiago; Tanaka, Leonardo Yuji; Bechara, Luiz R. Grassmann; de Sousa, Luis Gustavo Oliveira; Oliveira, Edilamar M; Ramires, Paulo Rizzo.

Clinics; 72 (5), 2017

OBJECTIVE: We aimed to determine whether aerobic training decreases superoxide levels, increases nitric oxide levels, and improves endothelium-dependent vasodilation in the aortas of spontaneously hypertensive rats. METHODS: Spontaneously hypertensive rats (SHR) and Wistar Kyoto rats (WKY) were distribu...

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