Results: 4

Serological profile of John Cunningham virus (JCV) in patients with multiple sclerosis

Arq. neuropsiquiatr; 76 (9), 2018
ABSTRACT Treatment options for multiple sclerosis (MS) have changed over the last few years, bringing about a new category of drugs with more efficient profiles. However, these drugs have come with a whole new profile of potential adverse events that neurologists have to learn well and quickly. One of th...

Multiple sclerosis risk perception and acceptance for Brazilian patients

Arq. neuropsiquiatr; 76 (1), 2018
ABSTRACT The perception of multiple sclerosis (MS) severity and risk associated with therapies might influence shared decision making in different countries. We investigated the perception of MS severity and factors associated with risk acceptance in Brazil in 96 patients with relapsing-remitting MS usin...

Experiencia local con natalizumab en pacientes con enfermedad de Crohn refractaria a anti-TNF: casos clínicos

Rev. méd. Chile; 145 (4), 2017
Anti-tumor necrosis factor-α (TNF) agents have dramatically changed the management of Crohn’s Disease (CD). However, a significant number of these patients do not respond at all or cease to respond to antibodies against TNF. In this clinical situation, the options include intensification of anti-TN...

Safety of switching from natalizumab straight into fingolimod in a group of JCV-positive patients with multiple sclerosis

Arq. neuropsiquiatr; 74 (8), 2016
ABSTRACT Objective To assess safety of the switch between natalizumab and fingolimod without a washout period. Methods Prospective data on 25 JCV positive patients who underwent this medication switch were collected and analyzed. Results After a median period of nine months from the medication swit...