LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Formulation, characterization and in vivo evaluation of novel edible dosage form containing nebivolol HCl

Vijayanand, Pujari; Patil, Jagadevappa; Reddy, Manda Venkata.

Braz. j. pharm. sci; 52 (1), 2016

ABSTRACT The objective of this investigation was to develop a novel oral edible gel dosage form for nebivolol hydrochloride, with suitable rheological characteristics that can provide a means of administering the drug to dysphagic and geriatric patients. Edible gels were prepared using low acetylated gel...

Nebivolol/análisis, Trastornos de Deglución/prevención & control, Trastornos de Deglución/prevención & control, Química Farmacéutica, Formas de Dosificación

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Development of fast dispersing tablets of nebivolol: experimental and computational approaches to study formulation characteristics

Formulation of FDT (fast dispersing tablets) of nebivolol was optimized and evaluated using simplex lattice design (SLD). The influence of type and concentration of three disintegrants viz., Ac-Di-Sol, Primojel and Polyplasdone XL on hardness, friability and disintegration time of tablet was studied. Res...