Results: 8

Necrólisis epidérmica tóxica en una adolescente diagnosticada de trastorno bipolar II y tratada con lamotrigina

Resumen La necrólisis epidérmica tóxica es una enfermedad cutánea severa, la mayoría de las veces desencadenada como reacción adversa a medicamentos, con alta morbilidad y mortalidad. La lamotrigina, junto a otros medicamentos estabilizadores del ánimo, constituye la causa medicamentosa más frecu...

Renal histological alterations induced by acute exposure of titanium dioxide nanoparticles

Int. j. morphol; 37 (3), 2019
SUMMARY: Titanium dioxide nanoparticles (TiO2 NPs) are widely used in many commercial products, nanomedicine, agriculture, personal care products, different industries and pharmaceutical preparations with potential risk in human health and the environment. The current work was conducted to investigate th...

Use of derived adipose stem cells to reduce complications of cutaneous scarring in smokers. An experimental model in rats

Acta cir. bras; 34 (6), 2019
Abstract Purpose To evaluate the use of adipose-derived stem cells (ADSC) in reducing the necrosis area in an experimental model of cutaneous ischemic flap in rats submitted to subcutaneous nicotine injection to simulate a smoker patient. Methods In an experimental study, 30 rats were enrolled and di...

Warfarin-induced skin necrosis in a patient with protein S deficiency

An. bras. dermatol; 93 (4), 2018

Interferon-gamma-induced local leukocytoclastic vasculitis at the subcutaneous injection site

An. bras. dermatol; 91 (5,supl.1), 2016
Abstract Cutaneous reactions associated with interferons (IFNs) treatment are either localized or generalized. The most common presentation of localized reactions at IFNs injection site is usually an erythematous patch or plaque. Local leukocytoclastic vasculitis presenting with cutaneous necrosis is ext...

Cytotoxicity and genotoxicity of calcium silicate-based cements on an osteoblast lineage

Braz. oral res. (Online); 30 (1), 2016
Abstract Several calcium silicate-based biomaterials have been developed in recent years, in addition to Mineral Trioxide Aggregate (MTA). The aim of this study was to evaluate the cytotoxicity, genotoxicity and apoptosis/necrosis in human osteoblast cells (SAOS-2) of pure calcium silicate-based cements ...

Intoxicación por fósforo blanco: lesiones hepáticas

Durante los años 1980-1982, se estudió la epidemiología y las características clínicas de pacientes de este servicio intoxicados por fósforo clanco. Se revisaron un total de 40 casos, todos los cuales presentaron vómito y dolor espigástrico; 92.5% desarrollaron ictericia. La mortalidad fue del 25...