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Tubulointerstitial nephritis and uveitis syndrome in children: report of three cases

Pereira, Cátia; Gil, Joana; Leal, Inês; Costa-Reis, Patrícia; Silva, José Eduardo Esteves Da; Stone, Rosário.
J. bras. nefrol; 40 (3), 2018
ABSTRACT Tubulointerstitial nephritis and uveitis syndrome is a rare and probably underdiagnosed condition. Renal and ocular manifestations may not occur simultaneously, making the diagnosis more difficult. Nephritis may be asymptomatic; therefore, renal function evaluation is essential for diagnosis. Ur...
Nefritis Intersticial/diagnóstico, Nefritis Intersticial/tratamiento farmacológico, Uveítis/diagnóstico, Uveítis/tratamiento farmacológico
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Baicalein alleviates tubular-interstitial nephritis in vivo and in vitro by down-regulating NF-κB and MAPK pathways

Chen, Yan; Zheng, Yu; Zhou, Zhihong; Wang, Jinjun.
Braz. j. med. biol. res; 51 (10), 2018
Tubular-interstitial nephritis (TIN) is characterized by tubular cell damage and inflammatory lesions of kidneys. Baicalein (BAI) is a flavonoid compound found in the roots of Scutellaria baicalensis Georgi. The present study was undertaken to explore the anti-inflammatory and anti-oxidative effects of B...
Antiinflamatorios/administración & dosificación, Antioxidantes/administración & dosificación, Regulación hacia Abajo, Ensayo de Inmunoadsorción Enzimática, Flavanonas/administración & dosificación, Lipopolisacáridos, Sistema de Señalización de MAP Quinasas/efectos de los fármacos, FN-kappa B/efectos de los fármacos, FN-kappa B/metabolismo, Nefritis Intersticial/tratamiento farmacológico, Transducción de Señal/efectos de los fármacos
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