Introduction: Returning to work is an important cancer recovery milestone. Permanent colostomy can be required for rectal cancer treatment and can significantly impact well-being. We aimed to evaluate the impact of permanent colostomy on health-related quality of life and return to work in patients with ...
Introduction: Almost 25% of colorectal cancer (CRC) patients have synchronous colorectal liver metastasis (SCLM) coinciding with the disease diagnosis. Liver-first approach for the treatment of SCLM involves neoadjuvant chemotherapy, subsequent liver resection, and then primary tumor resection. This stra...
Colorectal cancer (CRC) is the third most prevalent cancer worldwide. Although improvements in detection and
treatment have been implemented; CRC incidence, prevalence, and mortality remain high, even in developed
countries. The risk of developing this cancer is related to poor eating habits, smoking, in...
Background: The surgery with total mesorectal excision recommended by R. J. Heald in 1982 is the gold standard. Rectal cancer (RC) surgery has a morbidity rate ranging from 6 to 35%, and it can cause functional issues such as sexual, urinary, and bowel dysfunction in the long term. Neoadjuvant chemoradio...
Background: Patients with colorectal cancer may seek the emergency department for symptoms related to chemotherapy and radiotherapy side effects as well as those from the disease itself and from surgery complications. Objectives: To establish the epidemiological and clinical profile of colorectal cancer ...
Abd-Elaziz, Osama;
Ali, Ramadan M;
Amin, Mohamed Farouk;
Fahmy, Ahmed M;
Elshorbagy, Shereen;
Mandour, Doaa;
Hemeda, Rehab;
Harb, Ola A;
Samir, Amr;
El-Hendawy, Elsayed I.
Background: The relative rarity of synchronous para-aortic lymph node (PALN) metastasis (SPM) and metachronous PALN recurrence (MPR) in colorectal carcinoma (CRC) patients leads to a limited number of studies on patient management, and no treatment guidelines have been established to date. Objective: To ...
Colorectal cancer is the 4thcause of cancer death; with considering the growth process of this cancer and the necessity of early diagnosis, the purpose of the research is to state the LncRNA 00970, LncRNA UCAI,and the Wntgene before and after the treatment by 5-Azacytidine epigenetic medi...
Técnicas In Vitro/métodos,
Azacitidina/análisis,
Biomarcadores,
ADN/análisis,
Diagnóstico Precoz,
Neoplasias Colorrectales/tratamiento farmacológico,
ARN Largo no Codificante/efectos de los fármacos,
Genes,
Epigenómica,
Línea Celular/efectos de los fármacos,
Neoplasias del Colon/diagnóstico,
Azacitidina/antagonistas & inhibidores,
Neoplasias Colorrectales/mortalidad,
Neoplasias Colorrectales/terapia,
ARN Largo no Codificante,
Neoplasias del Colon/tratamiento farmacológico,
Neoplasias del Colon/terapia
Background: Anatomopathological staging is the primary method to determine the prognosis of patients with colorectal carcinoma (CRC). However, new tools have been developed that can complement it, such as the analysis of the elevation of systemic inflammatory markers. Objective: To evaluate the impact o...
Introduction: The Covid-19 pandemic has had an important impact on colorectal cancer surgery, for hospital resources had to be redistributed in favour of Covid-19 patients. The aim of the present study is to analyze our results in colorectal oncologic surgery during the Covid-19 pandemic in patients with...
Background: Globally, 1,096,601, 704,376, and 48,541 new colon, rectum, and anus cancer cases were recorded in 2018, respectively. Besides, 551,269, 310,394 and 19,129 cases of colon, rectum, and anus cancer deaths occurred in the same year. As a result, these cancers ranked in the third level of cancer ...