Expression of Ki-67 and P16 INK4a in chemically-induced perioral squamous cell carcinomas in mice
Rev. Col. Bras. Cir; 43 (2), 2016
ABSTRACT Objective: to evaluate the influence of Ki-67 and P16INK4a proteins immunohistochemical expressions on the clinical and morphological parameters of perioral squamous cell carcinoma induced with 9,10-dimethyl-1,2-benzanthracene (DMBA) in mice. Methods: we topically induced the lesions in the or...
Carcinoma de Células Escamosas/inducido químicamente, Carcinoma de Células Escamosas/metabolismo, Inhibidor p16 de la Quinasa Dependiente de Ciclina/biosíntesis, Antígeno Ki-67/biosíntesis, Ratones, Neoplasias de la Boca/inducido químicamente, Neoplasias de la Boca/metabolismo, Neoplasias Experimentales/inducido químicamente, Neoplasias Experimentales/metabolismo