MicroRNA-424-5p inhibits the proliferation, migration, and invasion of nasopharyngeal carcinoma cells by decreasing AKT3 expression
Braz. j. med. biol. res; 53 (7), 2020
This study examined the expression and potential mechanism of microRNA (miRNA)-424-5p in nasopharyngeal carcinoma (NPC). NPC tissues were collected from 40 patients who were enrolled in the study, and skin samples were collected from 26 healthy subjects during plastic surgery as controls. We performed va...
Western Blotting, Línea Celular Tumoral, Movimiento Celular, Proliferación Celular, Regulación Neoplásica de la Expresión Génica, MicroARNs/genética, MicroARNs/metabolismo, Carcinoma Nasofaríngeo/genética, Carcinoma Nasofaríngeo/metabolismo, Neoplasias Nasofaríngeas/genética, Neoplasias Nasofaríngeas/metabolismo, Invasividad Neoplásica, Proteínas Proto-Oncogénicas c-akt/genética, Proteínas Proto-Oncogénicas c-akt/metabolismo, Reacción en Cadena en Tiempo Real de la Polimerasa, Transducción de Señal