Results: 5

Proteínas mir-203a-3p e mmp-2 são altamente expressas em células tumorais circulantes de pacientes com carcinoma pancreático

ABCD (São Paulo, Impr.); 34 (4), 2021
RESUMO -RACIONAL: O adenocarcinoma ductal do pâncreas é a quarta causa de morte associada ao câncer mais comum no mundo ocidental. A presença de células tumorais circulantes (CTCs) pode ser considerada um potencial fator prognóstico, visto que essas células representam a progressão tumoral, permi...

HtrA1 suppresses the growth of pancreatic cancer cells by modulating Notch-1 expression

Braz. j. med. biol. res; 52 (1), 2019
Pancreatic cancer is well known to be the most deadly malignancy with the worst survival rate of all cancers. High temperature requirement factor A1 (HtrA1) plays an important role in cancer cell proliferation, migration, apoptosis, and differentiation. This study aimed to explore the function of HtrA1 i...

Cáncer de páncreas: alteraciones genéticas, cambios morfológicos y sus implicaciones terapéuticas

Med. leg. Costa Rica; 35 (1), 2018
Resumen El cáncer de páncreas es una enfermedad mortal, principalmente porque se descubre muy tarde y es muy resistente a la quimioterapia y radioterapia. El tipo más común de cáncer de páncreas (más del 90%) se desarrolla a partir de las células exocrinas del páncreas y se denomina adenocarcino...

Knockdown of ZFR suppresses cell proliferation and invasion of human pancreatic cancer

Biol. Res; 49 (), 2016
BACKGROUND: Zinc finger RNA binding protein (ZFR) is involved in the regulation of growth and cancer development. However, little is known about ZFR function in pancreatic cancer. METHODS: Herein, to investigate whether ZFR is involved in tumor growth, Oncomine microarray data was firstly used to evaluat...