LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Response to cytotoxic chemotherapy and overall survival in non-small cell lung cancer patients with positive or negative ERCC1 expression

Honma, Helen Naemi; Perroud Jr, Maurício Wesley; Morcillo, André Moreno; Vassallo, José; Zambon, Lair.

J. bras. pneumol; 44 (3), 2018

Antineoplásicos/uso terapéutico, Carcinoma de Pulmón de Células no Pequeñas/química, Carcinoma de Pulmón de Células no Pequeñas/tratamiento farmacológico, Carcinoma de Pulmón de Células no Pequeñas/mortalidad, Cisplatino/uso terapéutico, Proteínas de Unión al ADN/análisis, Endonucleasas/análisis, Inmunohistoquímica, Neoplasias Pulmonares/química, Neoplasias Pulmonares/tratamiento farmacológico, Neoplasias Pulmonares/mortalidad, Paclitaxel/uso terapéutico, Factores de Tiempo, Resultado del Tratamiento

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Lung cancer biopsy: Can diagnosis be changed after immunohistochemistry when the H&E-Based morphology corresponds to a specific tumor subtype?

Bernardi, Fabiola Del Carlo; Bernardi, Marcela Del Carlo; Takagaki, Teresa; Siqueira, Sheila Aparecida Coelho; Dolhnikoff, Marisa.

Clinics; 73 (), 2018

OBJECTIVES: Advancements in non-small cell lung cancer treatment based on targeted therapies have made the differentiation between adenocarcinoma and squamous cell carcinoma increasingly important. Pathologists are challenged to make the correct diagnosis in small specimens. We studied the accuracy of an...

Adenocarcinoma/química, Adenocarcinoma/patología, Biomarcadores de Tumor/análisis, Biopsia, Carcinoma de Pulmón de Células no Pequeñas/patología, Carcinoma de Células Escamosas/química, Carcinoma de Células Escamosas/patología, Diagnóstico Diferencial, Inmunohistoquímica, Neoplasias Pulmonares/química, Neoplasias Pulmonares/patología, Estudios Retrospectivos

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Detection of sputum cofilin-1 as indicator of malignancy

Rangel, M P; Antonangelo, L; Acencio, M M P; Faria, C S; de Sá, V K; Leão, P S; Farhat, C; Fabro, A T; Longatto Filho, A; Reis, R M; Takagaki, T; Capelozzi, V L.

Braz. j. med. biol. res; 51 (8), 2018

Cofilin-1 (CFL1), a small protein of 18 kDa, has been studied as a biomarker due to its involvement in tumor cell migration and invasion. Our aim was to evaluate CFL1 as an indicator of malignancy and aggressiveness in sputum samples. CFL1 was analyzed by ELISA immunoassay in the sputum of 73 lung cancer...

Biomarcadores de Tumor/análisis, Carcinoma de Células Escamosas/química, Carcinoma de Células Escamosas/mortalidad, Carcinoma de Células Escamosas/patología, Estudios de Casos y Controles, Proliferación Celular, Cofilina 1/análisis, Ensayo de Inmunoadsorción Enzimática, Neoplasias Pulmonares/química, Neoplasias Pulmonares/mortalidad, Neoplasias Pulmonares/patología, Invasividad Neoplásica, Estadificación de Neoplasias, Pronóstico, Curva ROC, Sensibilidad y Especificidad, Esputo/química

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