Results: 45

Development and evaluation of flubendazole inhalable nanoparticles for lung cancer treatmen

Lung cancer is the leading cause of cancer-related death. In addition to new innovative approaches, practical strategies that improve the efficacy of already available drugs are urgently needed. Inhalable administration of chemotherapy is a promising alternative to increase efficacy, reduce toxicity, and...

Morphine promotes migration and lung metastasis of mouse melanoma cells

Braz. J. Anesth. (Impr.); 73 (4), 2023
Abstract Background Morphine is an analgesic agent used for cancer pain management. There have been recent concerns that the immunosuppressant properties of morphine can also promote cancer metastasis. Morphine is an agonist for toll like receptor 4 (TLR4) that has a dual role in cancer development. The...

Cytotoxic activity of ethanolic extracts of Lippia graveolens HBK leaves and stem against lung cancer cell line SK-LU-1

Lippia graveolens HBK (Verbenaceae) is an aromatic herb of economic importance in Mexico, known as oregano. The leaves are used as condiments, and people use this species for respiratory and digestive disorders. The aim of this work was to evaluate the cytotoxic effect of eth...

Nivolumab en cáncer de pulmón de células no pequeñas en segundo línea tratamiento

El presente informe es producto del trabajo colaborativo de la Comisión Nacional de Evaluación de Tecnologías de Salud (CONETEC), dependiente del Ministerio de Salud de la Nación y creada por RM N° 623/2018. La CONETEC realiza evaluaciones y emite recomendaciones a la autoridad sanitaria sobre la in...

Revisión bibliográfica sobre la COVID 19 en pacientes con cáncer de pulmón
Bibliographic review on COVID 19 in patients with lung cancer

Rev. medica electron; 43 (1), 2021
RESUMEN La COVID 19 es una enfermedad pandémica producida por el virus SARS-CoV-2, tiene dentro de los grupos vulnerables al cáncer de pulmón por presentar una inmunodepresión adquirida por los tratamientos oncoespecíficos administrados y esto conlleva a una mayor exposición a complicaciones si se ...

Qualidade de vida relacionada à saúde de pessoas com câncer de pulmão avançado: um estudo qualitativo

Introdução: O câncer de pulmão é o tipo de câncer com a maior taxa mundial de mortalidade entre homens e o segundo entre mulheres. Apesar da sua relevância para a saúde pública, ainda falta compreender a vivência das pessoas acometidas pelo câncer de pulmão avançado. Objetivo: Compreender o ...

Which Tyrosine Kinase Inhibitor Must We Apply Before? A Case Report of Crizotinib-resistant Patient with Concomitant EGFR and EML4-ALK Gene Mutations

West Indian med. j; 69 (3), 2021
ABSTRACT The concomitant epidermal growth factor receptor (EGFR) mutation and anaplastic lymphoma kinase (ALK) translocations in lung adenocancers are very rare scenarios. Until now, 42 cases described in the literature have all been treated by different drugs. There is no overall consensus regarding the...

Melittin suppresses growth and induces apoptosis of non-small-cell lung cancer cells via down-regulation of TGF-β-mediated ERK signal pathway

Braz. j. med. biol. res; 54 (2), 2021
The purpose of this study was to investigate the anti-cancer effect of melittin on growth, migration, invasion, and apoptosis of non-small-cell lung cancer (NSCLC) cells. This study also explored the potential anti-cancer mechanism of melittin in NSCLC cells. The results demonstrated that melittin suppre...