LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Red propolis and L-lysine on angiogenesis and tumor growth in a new model of hamster cheek pouch inoculated with Walker 256 tumor cells

Juanes, Camila de Carvalho; Souza, Susana Moreira de; Braga, Vanessa Nogueira Lages; Barreto, Francisco Stefânio; Aguiar, Gisele Rocha; Pimentel, Kleison Douglas Gomes; Fechine, Francisco Vagnaldo; Dornelas, Conceição Aparecida.

Einstein (Säo Paulo); 17 (2), 2019

ABSTRACT Objective: To evaluate the effect of red propolis and L-lysine on angiogenesis and tumor growth in a new model of hamster cheek pouch inoculated with Walker 256 tumor cells. Methods: The study consisted of two experiments with four groups each (total: 57 hamsters). In the experiment 1, the ani...

Inhibidores de la Angiogénesis/uso terapéutico, Antioxidantes, Carcinoma 256 de Walker/irrigación sanguínea, Mejilla, Cricetinae, Lisina/uso terapéutico, Mesocricetus, Modelos Animales, Neoplasias de la Boca/irrigación sanguínea, Neoplasias de la Boca/inducido químicamente, Neoplasias de la Boca/tratamiento farmacológico, Neovascularización Patológica/tratamiento farmacológico, Própolis/uso terapéutico, Resultado del Tratamiento, Aumento de Peso

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Expression of Ki-67 and P16 INK4a in chemically-induced perioral squamous cell carcinomas in mice

ABSTRACT Objective: to evaluate the influence of Ki-67 and P16INK4a proteins immunohistochemical expressions on the clinical and morphological parameters of perioral squamous cell carcinoma induced with 9,10-dimethyl-1,2-benzanthracene (DMBA) in mice. Methods: we topically induced the lesions in the or...